Results 1 to 10 of about 19,991 (204)
Administration of L-Type Bovine Spongiform Encephalopathy to Macaques to Evaluate Zoonotic Potential [PDF]
We administered L-type bovine spongiform encephalopathy prions to macaques to determine their potential for transmission to humans. After 75 months, no clinical symptoms appeared, and prions were undetectable in any tissue by Western blot or ...
Morikazu Imamura +9 more
doaj +2 more sources
Improving Clinical Diagnosis of Transmissible Spongiform Encephalopathies in Sheep: Which Signs Are Important? [PDF]
Scrapie is a notifiable transmissible spongiform encephalopathy (TSE) in sheep that relies on clinical examinations for reporting suspects. A short examination protocol was used in 1002 sheep to define clinical markers suggestive of scrapie.
Timm Konold, Laura J. Phelan
doaj +2 more sources
Bovine spongiform encephalopathy [PDF]
T A, Holt, J, Phillips
+19 more sources
Experimental bovine spongiform encephalopathy infection in rabbits [PDF]
The aim of our work was to determine the sensitivity of rabbits to the C-BSE pathogen in the first passage, to obtain a laboratory model on rabbits to study the C-BSE pathogen.
Nadtochey Grigory +2 more
doaj +1 more source
Animal prion diseases: A review of intraspecies transmission [PDF]
Animal prion diseases are a group of neurodegenerative, transmissible, and fatal disorders that affect several animal species. The causative agent, prion, is a misfolded isoform of normal cellular prion protein, which is found in cells with higher ...
Mauro Julián Gallardo +1 more
doaj +1 more source
Eliminating Spiked Bovine Spongiform Encephalopathy Agent Activity from Heparin
US manufacturers, concerned about bovine spongiform encephalopathy (BSE), ceased marketing bovine heparin in the 1990s. Recent short supplies of safe porcine heparin suggest that reintroducing bovine heparin might benefit public health.
Cyrus Bett +5 more
doaj +1 more source
BSE-associated Prion-Amyloid Cardiomyopathy in Primates
Prion amyloidosis occurred in the heart of 1 of 3 macaques intraperitoneally inoculated with bovine spongiform encephalopathy prions. This macaque had a remarkably long duration of disease and signs of cardiac distress. Variant Creutzfeldt-Jakob disease,
Susanne Krasemann +11 more
doaj +1 more source
Objective The spread of bovine spongiform encephalopathy (BSE) agent to small ruminants is still a major issue in the surveillance of transmissible spongiform encephalopathies (TSEs). L-type bovine spongiform encephalopathy (L-BSE) is an atypical form of
Alessandra Favole +17 more
doaj +1 more source
Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study [PDF]
The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with respect to a possible atypical status.
Jacobs, J.G. +3 more
core +1 more source

