Results 11 to 20 of about 19,991 (204)

Strain Traits of Intracranially Administered L-Type Bovine Spongiform Encephalopathy Prions Are not Significantly Modified During Intraspecies Transmission in Cynomolgus Monkeys. [PDF]

open access: yesMicrobiol Immunol
ABSTRACT Among the three prion strains of bovine spongiform encephalopathy (BSE), classical BSE (C‐BSE) prions are known causative agents of variant Creutzfeldt–Jakob disease. By contrast, human infections with L‐type (L‐) or H‐type (H‐) BSE prions have not been reported.
Hagiwara K   +8 more
europepmc   +2 more sources

Epidemiology of progressive intellectual and neurological deterioration in UK children. [PDF]

open access: yesDev Med Child Neurol
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Verity CM   +3 more
europepmc   +2 more sources

Spongiform Encephalopathy in a Miniature Zebu

open access: yesEmerging Infectious Diseases, 2006
The first case of spongiform encephalopathy in a zebu (Bos indicus) was identified in a zoo in Switzerland. Although histopathologic and immunohistochemical analyses of the central nervous system indicated a diagnosis of bovine spongiform encephalopathy (
Torsten Seuberlich   +8 more
doaj   +1 more source

TSE pathogenesis in cattle and sheep [PDF]

open access: yes, 2008
Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts ...
Bossers, A.   +2 more
core   +3 more sources

Susceptibility of European red deer (Cervus elaphus elaphus) to alimentary challenge with bovine spongiform encephalopathy.

open access: yesPLoS ONE, 2015
European red deer (Cervus elaphus elaphus) are susceptible to the agent of bovine spongiform encephalopathy, one of the transmissible spongiform encephalopathies, when challenged intracerebrally but their susceptibility to alimentary challenge, the ...
Mark P Dagleish   +15 more
doaj   +1 more source

Jellyfish Collagen: A Biocompatible Collagen Source for 3D Scaffold Fabrication and Enhanced Chondrogenicity

open access: yesMarine Drugs, 2021
Osteoarthritis (OA) is a multifactorial disease leading to degeneration of articular cartilage, causing morbidity in approximately 8.5 million of the UK population.
Zara Ahmed   +6 more
doaj   +1 more source

Differentiation of ruminant transmissible spongiform encephalopathy isolate types, including bovine spongiform encephalopathy and CH1641 scrapie [PDF]

open access: yes, 2010
With increased awareness of the diversity of transmissible spongiform encephalopathy (TSE) strains in the ruminant population, comes an appreciation of the need for improved methods of differential diagnosis. Exposure to bovine spongiform encephalopathy (
Bossers, A.   +5 more
core   +2 more sources

Molecular Discrimination of Sheep Bovine Spongiform Encephalopathy from Scrapie

open access: yesEmerging Infectious Diseases, 2011
Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrPSc from sheep BSE is extremely resistant to denaturation.
Laura Pirisinu   +9 more
doaj   +1 more source

Elaboration of a new framework for fine-grained epidemiological annotation

open access: yesScientific Data, 2022
Measurement(s) Precision/Recall • Annotator aggreement Technology Type(s) Expert annotation • Kappa’s coefficient • Natural Language Processing Sample Characteristic - Organism Animal • African swine fever virus • Avian influenza • Foot-and-mouth disease
Sarah Valentin   +5 more
doaj   +1 more source

An overview of animal prion diseases

open access: yesVirology Journal, 2011
Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion diseases is associated with the accumulation of aggregates of misfolded conformers of host-encoded cellular prion ...
Imran Muhammad, Mahmood Saqib
doaj   +1 more source

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