Results 51 to 60 of about 381,364 (391)

The spectrum of disease in chronic traumatic encephalopathy.

open access: yesBrain : a journal of neurology, 2013
Chronic traumatic encephalopathy is a progressive tauopathy that occurs as a consequence of repetitive mild traumatic brain injury. We analysed post-mortem brains obtained from a cohort of 85 subjects with histories of repetitive mild traumatic brain ...
A. Mckee   +22 more
semanticscholar   +1 more source

Sepsis-associated encephalopathy: a vicious cycle of immunosuppression

open access: yesJournal of Neuroinflammation, 2020
Sepsis-associated encephalopathy (SAE) is commonly complicated by septic conditions, and is responsible for increased mortality and poor outcomes in septic patients.
C. Ren   +4 more
semanticscholar   +1 more source

Validity of the 2014 traumatic encephalopathy syndrome criteria for CTE pathology

open access: yesAlzheimer's & Dementia, 2021
Validity of the 2014 traumatic encephalopathy syndrome (TES) criteria, proposed to diagnose chronic traumatic encephalopathy (CTE) in life, has not been assessed.
Jesse B. Mez   +25 more
semanticscholar   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

Copper deposition in Wilson’s disease causes male fertility decline by impairing reproductive hormone release through inducing apoptosis and inhibiting ERK signal in hypothalamic-pituitary of mice

open access: yesFrontiers in Endocrinology, 2022
Wilson’s disease (WD) is an autosomal recessive disorder of copper metabolism characterized by liver and central nervous system dysfunction. Considerable evidence suggests that infertility is also very common in male patients with WD, but the exact ...
Tingting Wang   +7 more
doaj   +1 more source

DNM1 encephalopathy: A new disease of vesicle fission. [PDF]

open access: yes, 2017
ObjectiveTo evaluate the phenotypic spectrum caused by mutations in dynamin 1 (DNM1), encoding the presynaptic protein DNM1, and to investigate possible genotype-phenotype correlations and predicted functional consequences based on structural modeling ...
Campbell, Colleen A   +38 more
core   +2 more sources

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

open access: yesJournal of Neuropathology and Experimental Neurology, 2009
Since the 1920s, it has been known that the repetitive brain trauma associated with boxing may produce a progressive neurological deterioration, originally termed dementia pugilistica, and more recently, chronic traumatic encephalopathy (CTE).
A. Mckee   +9 more
semanticscholar   +1 more source

Sepsis-Associated Encephalopathy: From Delirium to Dementia?

open access: yesJournal of Clinical Medicine, 2020
Sepsis is a major cause of death in intensive care units worldwide. The acute phase of sepsis is often accompanied by sepsis-associated encephalopathy, which is highly associated with increased mortality.
Ha-Yeun Chung   +3 more
semanticscholar   +1 more source

Hepatic encephalopathy

open access: yesSaudi Journal of Gastroenterology, 2012
Chronic liver disease and cirrhosis affect hundreds of millions of patients all over the world. The majority of patients with cirrhosis will eventually develop complications related to portal hypertension. One of these recurrent and difficult to treat complications is hepatic encephalopathy.
Wissam Bleibel, Abdullah M. S. Al-Osaimi
openaire   +3 more sources

Yi-nao-jie-yu Prescription Exerts a Positive Effect on Neurogenesis by Regulating Notch Signals in the Hippocampus of Post-stroke Depression Rats

open access: yesFrontiers in Psychiatry, 2018
Post-stroke depression (PSD) is one of the most frequent complications of stroke. The Yi-nao-jie-yu prescription (YNJYP) is an herbal prescription widely used as a therapeutic agent against PSD in traditional Chinese medicine.
Huiling Tian   +10 more
doaj   +1 more source

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