Results 61 to 70 of about 62,356 (240)

Improvement of optimization of the drive design for laser scanners based on the analysis of characteristics of scanning devices in construction industry

Омский научный вестник
A laser scanning is a promising method of control in construction, providing high accuracy and speed of measurements. Terrestrial laser scanning is one of the key tools within the framework of Building Information Modeling technology, enabling the ...
A. Yu. Turybrin, A. V. Bubnov, A. N. Chetverik   +2 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Deep Learning-Based MRI Brain Tumor Segmentation With EfficientNet-Enhanced UNet

IEEE Access
Medical image segmentation plays a critical role in the field of medical image processing. Precisely delineating brain tumor areas from multimodal MRI scans is crucial for clinical diagnosis and predicting patient outcomes. However, challenges arise from
Pradeep Kumar Tiwary, Prashant Johri, Alok Katiyar, Mayur Kumar Chhipa   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Computationally Efficient Single Layer Transformer Convolutional Encoder for Accurate Price Prediction of Agriculture Commodities

IEEE Access
Predicting the accurate future price of the agricultural crops is important to avoid overproduction or shortages in the food supply chain. To obtain accurate predictions, the process usually involves large and complex datasets, which would add to ...
Caceja Elyca Anak Bundak, Mohd Amiruddin Abd Rahman, Nurin Syazwina Mohd Haniff, Nur Syaiful Afrizal, Khairul Adib Yusof, Muhammad Khalis Abdul Karim, Md Shuhazlly Mamat, Romi Fadillah Rahmat   +7 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Brain tumor segmentation by deep learning transfer methods using MRI images

Компьютерная оптика
Brain tumor segmentation is one of the most challenging tasks of medical image analysis. The diagnosis of patients with gliomas is based on the analysis of magnetic resonance images and manual segmentation of tumor boundaries.
E.Y. Shchetinin
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source