Results 71 to 80 of about 67,964 (199)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Corpus Augmentation for Neural Machine Translation with Chinese-Japanese Parallel Corpora

open access: yesApplied Sciences, 2019
The translation quality of Neural Machine Translation (NMT) systems depends strongly on the training data size. Sufficient amounts of parallel data are, however, not available for many language pairs.
Jinyi Zhang, Tadahiro Matsumoto
doaj   +1 more source

The Music Encoding Initiative As A Document-Encoding Framework. [PDF]

open access: yes, 2011
[TODO] Add abstract here.
Andrew Hankinson   +2 more
openaire   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The aspect of vector control using the asynchronous traction motor in locomotives

open access: yesTransport, 2009
The article examines curves controlling asynchronous traction motors increasingly used in locomotive electric drives the main task of which is to create a tractive effort‐speed curve of an ideal locomotive Fk = f(v), including a hyperbolic area the curve
Lionginas Liudvinavičius   +3 more
doaj  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Multi-step wind power prediction based on patch-wise attention mechanism

open access: yes电力工程技术
Effective feature representation is crucial for machine learning-based wind power prediction. Existing studies typically employ point-wise attention mechanisms to learn features at each time step of the wind power time series.
Bixing REN   +4 more
doaj   +1 more source

STEPNet: A Spatial and Temporal Encoding Pipeline to Handle Temporal Heterogeneity in Climate Modeling Using AI: A Use Case of Sea Ice Forecasting

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Sea ice forecasting remains a challenging topic due to the complexity of understanding its driving forces and modeling its dynamics. This article contributes to the expanding literature by developing a data-driven, artificial intelligence (AI)-based ...
Sizhe Wang, Wenwen Li, Chia-Yu Hsu
doaj   +1 more source

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