Results 81 to 90 of about 1,255,561 (338)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

open access: yesAdvanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam   +5 more
wiley   +1 more source

A Pseudo‐Mytilus Edulis Foot Protein‐Based Hydrogel Adhesive with Osteo‐Vascular‐Immune Coupling Effects for Osteoporotic Bone‐Implant Integration

open access: yesAdvanced Materials, EarlyView.
Inspired by mussel proteins, YDC‐Gel‐Zn is a smart bone glue designed for osteoporotic implants. It adheres strongly to both metal implants and bone for initial fixation. In osteoporosis's inflammatory environment, it sequentially releases zinc ions and therapeutic peptides: the zinc modulates immune cells to reduce inflammation, while the peptides ...
Wentao Wang   +9 more
wiley   +1 more source

Archeo‐Inspiration from the Cultural History of Glass: Historic Accounts, Anecdotes and Hard Facts as Challenges to Modern Material Science

open access: yesAdvanced Materials, EarlyView.
Glass, historically valued for its purity and durability, has long inspired artists and societies. This article introduces the concept of “Archeo‐Inspiration”, drawing on cultural and historical contexts of glass to guide future material innovations.
Eva von Contzen   +3 more
wiley   +1 more source

Tailored Xenogeneic‐Free Polymer Surface Promotes Dynamic Migration of Intestinal Stem Cells

open access: yesAdvanced Materials, EarlyView.
This study introduces a PoLymer‐coated Ultra‐stable Surface (PLUS), a nitrogen plasma‐treated poly(ethyleneglycoldimethacrylate), as a stable xenogeneic‐free platform for intestinal stem cell culture. PLUS enhances cell attachment, supports actin‐driven migration, and retains functionality after 3 years of storage. Promoting cytoskeletal reorganization,
Seonghyeon Park   +13 more
wiley   +1 more source

A Comparative Study of the Encyclopedia Compilation Process in the Encyclopedia World of Islam & Encyclopedia of Islam – Leiden

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2015
Purpose: the present paper compares two reference books the Encyclopedia World of Islam &  Encyclopedia  of Islam– Leiden  with regard to the whole process of compiling the encyclopedia, and to conduct an evaluative content analysis .
seyyed ahmad hosseinzadeh   +1 more
doaj  

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

open access: yesAdvanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li   +19 more
wiley   +1 more source

The Criterion of Incorporeal and Material Things in the Philosophy of Plotinus and Mūllā Sadrā

open access: yesMetaphysics, 2010
Incorporeal being consists of immaterial things such as intellect and soul. Also The One, in Plotinus' philosophy, and Independent and Rich Existence (Necessary Being), in Mullā Sadrā's philosophy, are incorporeal and immaterial.
R Akbarian, T Karami
doaj  

Impossibles encyclopédies

open access: yesItinéraires, 2016
R. E. Koçu was without doubt one of the most distinguished scholars on Istanbul. He seeked to describe with the rarest details the strange habits regarding the social life of Old Istanbul within the context of Ottoman and Early Republican History.
Timour Muhidine
doaj   +1 more source

CD207‐Positive Dendritic Cells Promote Emphysema Through CD8+ T Cell Pathway in Chronic Obstructive Pulmonary Disease

open access: yesAdvanced Science, EarlyView.
CD207+ dendritic cells (DCs) drive emphysema by promoting CD8⁺ T cell cytotoxicity via Birbeck granule‐dependent MHC‐I antigen presentation. This DC subset is expanded by cigarette smoke‐induced oxidative stress, which triggers granulocyte‐macrophage colony‐stimulating factor (GM‐CSF) release from airway epithelium.
Shurui Xuan   +10 more
wiley   +1 more source

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