Results 101 to 110 of about 599,480 (261)

Project HOPE: Survey of South Florida Residents’ Knowledge and Opinions on End-of-Life Issues

, 2010
Objective. To gain an understanding of knowledge and attitudes among the general population regarding end of life issues and hospice care among a convenience sample of South Florida residents. Background.
Ruff, Heather, Jacobs, Robin J., Fernandez, M. Isabel, Bowen, G. Stephen   +3 more
core  

MJM MedTalks (S02E09+10)

McGill Journal of Medicine
McGill Journal of Medicine (MJM) Podcast Series, MJM MedTalks, interviews members of the medical and health sciences community from McGill, and beyond to gain insights into their careers, research, advocacy, and more.
Maryia Samuel, Veronique Fraser, Blair Carl Schwartz, Samy Amghar, Vanessa Ross, Katherine Lan, Susan Joanne Wang, Renée-Claude Bider   +7 more
doaj  

End-of-Life Issues in the Era of the COVID-19 Pandemic. [PDF]

Hanguk Hosupisu Wanhwa Uiryo Hakhoe Chi, 2020
Ghosh D, Gupta B.
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

"You Have to Do This When You're Healthy": An Introduction to Library Involvement in Programming on End-of-Life Issues

While the library literature shows that librarians work to address information needs about end-of-life issues, no systematic research on library involvement in programming about these issues yet exists.
Irwin, Jarrod
core   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Ethical Issues at the End of Life [PDF]

Annals of Emergency Medicine, 2020
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Taking care of Muslim patients: spiritual, gender, & end-of-life issues in focus

, 2016
Tuesday, February 9, 2016; noon to 1 p.m.; Room D1.602. "Taking Care of Muslim Patients: Spiritual, Gender, & End-of-Life Issues in Focus". Aasim I. Padela, M.D., M.Sc., Director of the Initiative on Islam and Medicine, Program on Medicine & Religion ...
Padela, Aasim I.
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source