Results 81 to 90 of about 3,892,232 (280)

The ABCD of usability testing [PDF]

open access: yes, 2017
We introduce a methodology for tracking and auditing feedback, errors and suggestions for software packages. This short paper describes how we innovate on the evaluation mechanism, introducing an (Antecedent, Barrier, Consequence and Development) ABCD ...
De Paoli, Stefano   +2 more
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Ethical Issues in the End of Life Care for Cancer Patients in Iran

open access: yesIranian Journal of Public Health, 2013
Background: In the recent years, advances in medical technologies for end stage cancer patients’ care have affected the end-of-life decision-making in clinical practice and exposed oncologists to serious ethical dilemmas.
Mina Mobasher   +4 more
doaj   +2 more sources

Construction of family support program on end⁃of⁃life issues interaction between patients and their families

open access: yesHuli yanjiu, 2021
ObjectiveTo construct an interactive family support program on end⁃of⁃life issues between patients and their families.MethodsThe framework of the British Medical Research Council's intervention program was used as the methodological basis.Based on the ...
WANG Mengmeng, XU Tianmeng, YUE Peng
doaj  

Family Views of End-of-Life Care in Acute and Community Hospitals [PDF]

open access: yes, 2010
The Hospice friendly Hospitals Programme (HfH) commissioned this study to assess the quality of end-of-life care in acute and community hospitals from the perspectives of bereaved relatives.
Ciarán OBoyle, Siobhán McCarthy
core  

Convivial Decay:Entangled Lifetimes in a Geriatric Infrastructure [PDF]

open access: yes, 2016
This paper discusses the empirical case of an aging and obsolescent infrastructure supporting a space science mission that is currently approaching a known end.
Cohn, Marisa
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Design for manufacture and sustainability in new product development [PDF]

open access: yes, 2010
Design for manufacture is well recognised by industry and is about optimising design to aid production. Today there is a significant and growing trend of recognising what happens to a product once its user phase has finished.
De Coster, R   +3 more
core  

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