Results 71 to 80 of about 3,892,232 (280)
Revista Iberoamericana de BioéticaTerminally ill patients experience conditions of life that can become unbearable resulting in the wish to end their life prematurely. One way to end one’s life prematurely is by voluntary stopping of eating and drinking, however this can also be ...
Cíntia Pinho-Reis, Manuel Luís Capelas
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The Criminalization of Treating End of Life Patients with Risky Pain Medication and the Role of the Extreme Emergency Situation [PDF]
, 2007 This Note examines the legality of physicians treating patients near the end of life with risky pain medication, specifically during an extreme emergency situation.
Castellano, Gina
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Ethical issues associated with in-hospital emergency from the medical emergency team's perspective: a national survey [PDF]
, 2016 Medical Emergency Teams (METs) are frequently involved in ethical issues associated to in-hospital emergencies, like decisions about end-of-life care and intensive care unit (ICU) admission.
ALAMPI, DANIELA +13 more
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Ceaseless Toil? Health and Labor Supply of the Elderly in Rural China [PDF]
, 2003 Deborah Davis-Friedmann (1991) described the “retirement” pattern of the Chinese elderly in the prereform era as “ceaseless toil”: lacking sufficient means of support, the elderly had to work their entire lives.
Benjamin, Dwayne +2 more
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
BMC Palliative Care, 2010 Background The aim of this paper is to critically discuss some of the ethically controversial issues regarding continuous deep palliative sedation at the end of life that are addressed in the EAPC recommended framework for the use of sedation in ...
Juth Niklas +4 more
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Communication challenges in end-of-life decisions
Swiss Medical Weekly, 2020 With the progress in healthcare over recent decades and a growing life expectancy, discussions and decisions regarding end-of-life issues have become increasingly important. Especially in intensive care and emergency medicine there is a growing need of
Christoph Becker +3 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source