Results 51 to 60 of about 599,480 (261)

Older people living alone (OPLA) – non-kin-carers’ support towards the end of life: qualitative longitudinal study protocol

BMC Geriatrics, 2019
Background A growing number of older people, mainly women, live in single households. They represent a vulnerable group as staying at home may turn out challenging when care needs increase, particularly at the end of life.
Sabine Pleschberger, Elisabeth Reitinger, Birgit Trukeschitz, Paulina Wosko   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The development of a questionnaire to assess the attitudes of older people to end-of-life issues (AEOLI)

, 2005
Objectives: To develop an end-of-life attitudes questionnaire for use in a large community-based sample of older people. Design: Nominal groups and standardization of questions.
Blizard, R., Blanchard, M., King, M., Addington-Hall, J., Catt, S., Zis, M.   +5 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Language Variations in Describing Nutrition and Hydration Interventions in State Physician Orders for Life Sustaining Treatment Forms and the Implications for Advanced Dementia Patients

Palliative Medicine Reports
Background: Research suggests that language can impact medical decision-making, but few studies exist describing the variations in language to describe end-of-life nutrition and hydration interventions.
Sarah Rebecca Stephen
doaj   +3 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

End-of-life care in the United States: policy issues and model programs of integrated care

International Journal of Integrated Care, 2003
Background: End-of-life care financing and delivery in the United States is fragmented and uncoordinated, with little integration of acute and long-term care services.
Joshua M. Wiener, Jane Tilly
doaj   +3 more sources

Refusal of Oral Feeding and Nutrition or a Way to Speed Up Dying Without Asking Permission: Voluntarily Stopping of Eating and Drinking in the End of Life

Revista Iberoamericana de Bioética
Terminally ill patients experience conditions of life that can become unbearable resulting in the wish to end their life prematurely. One way to end one’s life prematurely is by voluntary stopping of eating and drinking, however this can also be ...
Cíntia Pinho-Reis, Manuel Luís Capelas
doaj   +1 more source

A Same-Sex Couple Copes With End-of-Life Issues: A Case Materials Guide

MedEdPORTAL, 2013
Medical students in the United States receive a median of only 5 hours of instruction on lesbian, gay, bisexual, and transgender–related health topics during medical school.
Colby Croft, Jonathan Pletcher, Valerie L. Fulmer, Robert C.T. Steele, Hollis Day, Carla L. Spagnoletti   +5 more
doaj   +1 more source