Results 61 to 70 of about 167,114,309 (280)

Evaluating complex interventions in end of life care : the MORECare statement on good practice generated by a synthesis of transparent expert consultations and systematic reviews [PDF]

open access: yes, 2013
Despite being a core business of medicine, end of life care (EoLC) is neglected. It is hampered by research that is difficult to conduct with no common standards.
Gunn Grande   +54 more
core   +4 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

End-of-life care in the United States: policy issues and model programs of integrated care

open access: yesInternational Journal of Integrated Care, 2003
Background: End-of-life care financing and delivery in the United States is fragmented and uncoordinated, with little integration of acute and long-term care services.
Joshua M. Wiener, Jane Tilly
doaj   +3 more sources

Refusal of Oral Feeding and Nutrition or a Way to Speed Up Dying Without Asking Permission: Voluntarily Stopping of Eating and Drinking in the End of Life

open access: yesRevista Iberoamericana de Bioética
Terminally ill patients experience conditions of life that can become unbearable resulting in the wish to end their life prematurely. One way to end one’s life prematurely is by voluntary stopping of eating and drinking, however this can also be ...
Cíntia Pinho-Reis, Manuel Luís Capelas
doaj   +1 more source

A Same-Sex Couple Copes With End-of-Life Issues: A Case Materials Guide

open access: yesMedEdPORTAL, 2013
Medical students in the United States receive a median of only 5 hours of instruction on lesbian, gay, bisexual, and transgender–related health topics during medical school.
Colby Croft   +5 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

End of life care: an educational pathway for community nurses. [PDF]

open access: yes, 2014
This article reports on an innovative educational pathway for district and community nurses aimed at enhancing confidence and competence in dealing with end of life care (EoLC). Nurses were aligned with a mentor from a specialist palliative care team and,
Steven, Alison   +3 more
core   +1 more source

End-of-life communication strategies for healthcare professionals: A scoping review

open access: yes, 2022
Background: Timely and effective communication about end-of-life issues, including conversations about prognosis and goals of care, are extremely beneficial to terminally ill patients and their families.
Molasiotis, A.   +3 more
core   +1 more source

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