Results 101 to 110 of about 66,863,659 (305)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A Reliable Routing Algorithm for Delay Sensitive Data in Body Area Networks [PDF]
Journal of Advances in Computer Engineering and Technology, 2018 Wireless body Area networks (WBANs) include a number of sensor nodes placed inside or on the human body to improve patient health and quality of life. Ensuring the transfer and receipt of data in sensitive data is a very important issue.
Mojgan ShariatmadariSerkani +2 more
doaj
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Rethinking the Design of the Internet: End to End Arguements vs. the Brave New World [PDF]
, 2000 This paper looks at the Internet and the changing set of requirements for the Internet that are 8oriented towards the consumer, and used for a wider set of purposes.
Clark, David, Blumenthal, Marjory
core
End-to-End Optimized Transmission over Dispersive Intensity-Modulated Channels Using Bidirectional Recurrent Neural Networks [PDF]
, 2019 We propose an autoencoding sequence-based transceiver for communication over dispersive channels with intensity modulation and direct detection (IM/DD), designed as a bidirectional deep recurrent neural network (BRNN).
Boris Karanov (17504196) +3 more
core +1 more source
End to End Development Engineering
Journal of Software Engineering and Applications, 2011 Raising software abstraction and re-use levels are key success factors for producing quality software products. Model-driven architecture (MDA) is an OMG initiative following this trend by mapping a conceptual model of application specified in platform independent model (PIM), to one or more platform specific models (PSM) automatically.
Abdelgaffar Hamed, Robert M. Colomb
openaire +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
End-to-End Optimization of Metasurfaces for Imaging with Compressed Sensing [PDF]
We present a framework for the end-to-end optimization of metasurface imaging systems that reconstruct targets using compressed sensing, a technique for solving underdetermined imaging problems when the target object exhibits sparsity (e.g., the object ...
Steven G. Johnson (137456) +5 more
core +3 more sources
End-to-End Call Establishment Delay Optimization
Dianxin kexue, 2013 From the detailed analysis of the current network signaling, the reason for the call setup delay in the network was researhed. And the call establishment delay shortening solution was also provided.
Cuiling Chen
doaj +2 more sources