Results 111 to 120 of about 66,863,659 (305)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

CAPES Newsletter January 2024 [PDF]

open access: yes
This is the January 2024 issue of the CAPES Newsletter containing relevant news and center ...
Center for Accelerating Practices to End Suicide (CAPES)
core   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

End-to-end Learning for Automomous Crop Row-following [PDF]

open access: yes, 2019
For robotic technology to be adopted within the agricultural domain, there is a need for low-cost systems that can be flexibly deployed across a wide variety of crop types, environmental conditions, and planting methods, without extensive re-engineering.
Richard James Donald Moore (17923826)   +2 more
core   +2 more sources

Resection Urethroplasty for Urethral Stricture: Preliminary Findings from a Tertiary Care Hospital of Central Nepal

open access: yesJournal of College of Medical Sciences-Nepal, 2019
Background: Urethral stricture is relatively common problem that we encounter in urological practice. As urethral stricture causes progressive narrowing of the urethral lumen, signs and symptoms of urinary  obstruction arise.
Sudeep Raj KC   +5 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

End-to-End Consistency of Multi-Tier Operations Across Mixed Replicated and Unreplicated Components [PDF]

open access: yes, 2018
While distributed applications need replication for the purposes of fault-tolerance, realistic and feasible deployments cannot afford to replicate every single component within the system.
Priya Narasimhan (5356850)   +1 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

End-to-end delay for the change of NCBR and vmax. [PDF]

open access: yes, 2018
End-to-end delay for the change of NCBR and vmax.
Hyun Jong Yang (5807309)   +1 more
core   +1 more source

Ubranch Conformer: Integrating Up-Down Sampling and Branch Attention for Speech Recognition

open access: yesIEEE Access
Conformer has become one of the most popular models in the field of automatic speech recognition, achieving superior speech recognition performance by integrating a convolutional module into Transformer. However, existing Conformer models face challenges
Yang Yang   +3 more
doaj   +1 more source

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