Results 121 to 130 of about 91,851,659 (299)
End-To-End 3D Facial Shape Reconstruction from an Unconstrained Image
, 2021 End-To-End 3D Facial Shape Reconstruction from an Unconstrained ...
Y Han (7708904) +3 more
core
End-to-end multimodal 16-day hatching eggs classification
, 2019 Sixteen-day hatching eggs are divided into fertile eggs, waste eggs, and recovered eggs. Because different categoriesmayhave the same characteristics, they are difficult to classify. Fewexisting algorithms can successfully solve this problem. To this end,
Zhen Peng (539724) +3 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Journal of Economy and TechnologyObjective: Little research has been done on the user-centered document ranking approach, especially in a crowdsourcing chart review environment. As the starting point of designing and implementing the next generation of Electronic Medical Record (EMR ...
Cheng Ye, Daniel Fabbri
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Mining prerequisite relations among learning objects
大数据, 2020 Prerequisite relation refers to the learning dependency between learning objects.Most previous works mined prerequisite relations in a pipelined way and heavily relied on hyperlinks,which lead to the accumulation of errors.To address these issues ...
Kexin MA +6 more
doaj