Results 81 to 90 of about 66,863,659 (305)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The End of End-to-End: Preserving the Architecture of the Internet in the Broadband Era [PDF]

open access: yesSSRN Electronic Journal, 2000
Author(s): Lemley, Mark A. | Abstract: In this paper, we address the question of "open access" and its relationship to the architecture of the Internet. It is our view that the extraordinary growth and innovation of the Internet depends crucially upon this architecture.
Lemley, Mark A., Lessig, Lawrence
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

End-to-end cost assessment of large particle private-wire services

open access: yesDianxin kexue, 2016
With the bandwidth of private-wire going up,end-to-end cost assessment of large particle private-wire service becomes more important.Based on the end-to-end bearer form and economic evaluation theory,a cost assessment model was presented,and supplemented
Minfeng ZHANG, Nan ZHOU
doaj   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

End-to-End Modeling for Abstractive Speech Summarization [PDF]

open access: yes
 In our increasingly interconnected world, where speech remains the most intuitive and natural form of communication, spoken language processing systems face a crucial challenge: they must do more than just categorize speech, they need to truly ...
Roshan Sharma (5968718)
core   +1 more source

Long-lasting and fast methylglyoxal-scavenging peptide CycK(Myr)R4E alleviates chronic pain in type 2 diabetic mice

open access: yesPAIN Reports
. Introduction:. Pathological levels of methylglyoxal (MG), a reactive dicarbonyl product of glucose, contribute to major neurological complications associated with type II diabetes, including chronic neuropathic pain.
Paramita Basu   +8 more
doaj   +1 more source

Early Outcomes of Aortic Coarctation Repair in Children not Suitable for Percutaneous Catheter Intervention [PDF]

open access: yesAl-Azhar International Medical Journal
Background: Aortic coarctation (CoA) is a congenital heart disease (CHD) marked by discrete or diffuse narrowing in the descending aorta at the juxta-ductal region.1 It represents 5-8% of all CHD.
Deyaa Aldin Mohamed   +3 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

VOIP End-To-End Security using S/MIME and a Security Toolbox [PDF]

open access: yes, 2014
Voice Over Internet Protocol (VOIP) is a rapidlygrowing Internet service for telephone communication. However, while it offers a number of cost advantages over traditional telephone service, it can pose a security threat, especially when used over public
Md. Shahidul Islm
core   +1 more source

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