Results 101 to 110 of about 7,379,857 (314)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Explaining the Status and Function of Imaginative Faculty in Rational Emission of Behavior and Action with an Emphasis on Mulla Sadra’s Doctrine of Soul [PDF]

اخلاق وحیانی, 2016
Ibn Sina explains the emission of the human conscious-rational action by practical reason utilization of imaginative faculty and the companionship of these two.
Mohammad-Hoseyn Vafa’iyan, Ahad Faramarz Gharamaleki   +1 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation [PDF]

, 2003
Cleavage and polyadenylation factor (CPF) is a multi-protein complex that functions in pre-mRNA 3'-end formation and in the RNA polymerase II (RNAP II) transcription cycle.
Sadowski, Martin, Kyburz, A., Kyburz, Andrea, Dichtl, B., Keller, W., Keller, Walter, Sadowski, M., Dichtl, Bernhard   +7 more
core   +2 more sources

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

Beilstein Journal of Nanotechnology, 2014
PVP-capped silver nanoparticles with a diameter of the metallic core of 70 nm, a hydrodynamic diameter of 120 nm and a zeta potential of −20 mV were prepared and investigated with regard to their biological activity.
Sebastian Ahlberg, Alexandra Antonopulos, Jörg Diendorf, Ralf Dringen, Matthias Epple, Rebekka Flöck, Wolfgang Goedecke, Christina Graf, Nadine Haberl, Jens Helmlinger, Fabian Herzog, Frederike Heuer, Stephanie Hirn, Christian Johannes, Stefanie Kittler, Manfred Köller, Katrin Korn, Wolfgang G. Kreyling, Fritz Krombach, Jürgen Lademann, Kateryna Loza, Eva M. Luther, Marcelina Malissek, Martina C. Meinke, Daniel Nordmeyer, Anne Pailliart, Jörg Raabe, Fiorenza Rancan, Barbara Rothen-Rutishauser, Eckart Rühl, Carsten Schleh, Andreas Seibel, Christina Sengstock, Lennart Treuel, Annika Vogt, Katrin Weber, Reinhard Zellner   +36 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Genre of khaghani’s elegies [PDF]

Literary Arts, 2016
 Abstract  Elegy in word is derived from Rasa-Yarso means weeping on dead people. It is also defined as enumerating deceased benefits and composing the poem about. Elegy is categorized into different parts as follows: 1. Courtier 2.
Alireza Shanazari
doaj  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Defining the “to” in end-to-end models [PDF]

, 2009
Robust models relating climate change to fish production require an adequate description of planktonic intermediaries between phytoplankton and fish in end-to-end models.
Davis, Cabell, Mitra, Aditee
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source