Results 251 to 260 of about 7,340,393 (314)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

CMR-derived left ventricular pressure-volume loops enhance individualized assessment of disease severity and prognosis in pulmonary arterial hypertension in adults. [PDF]

Physiol Rep
Castiglione A, Bergström E, Kjellström B, Rådegran G, Arheden H, Ostenfeld E.   +5 more
europepmc   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

What is end-stage knee osteoarthritis? A scoping and narrative review. [PDF]

Osteoarthr Cartil Open
Egerton T, Campbell PK.
europepmc   +1 more source

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Exploring barriers to and experiences of palliative and end-of-life care for people living with HIV: a cross-sectional survey. [PDF]

BMJ Open
Crooks J, Simpson-Greene C, Hughes L, Dreja L, Tweed M, Holt T, Brimacombe M, Jeneway R, Macrowan R, Hudson BF.   +9 more
europepmc   +1 more source

MFAP5⁺ synovial fibroblasts drive LOX upregulation to promote osteoarthritis progression. [PDF]

iScience
Wang L, Wei G, Ma F, Li X, Zhang H, Pan H, Meng Z, Yang S, Yang R, Dong J, Xiong X, Xu Z, Zhang B, Cheng H, Li B, Yang L, E X, Li X.   +17 more
europepmc   +1 more source

From Waste to Resource: Reframing End-of-Life Materials for a Circular Future: Within MSE Symposium Sustainable Reprocessing of End-of-Life Materials and Side Streams. [PDF]

Glob Chall
Jovičević-Klug M, Villa Gomez D, Brondin CA, Jovičević-Klug P.   +3 more
europepmc   +1 more source