Results 21 to 30 of about 207,096 (194)

Endemic Chagas Disease [PDF]

, 2009
Infections by Trypanosoma cruzi are transmitted commonly by triatomines, hematophagous insects adapted to anthropophilic behavior. With its potential enzootic presence for over 90 million years, Chagas disease in humans has been documented in 9 thousand-year-old mummies from the Atacama Desert.
Antonio Teixeira, Rubens Nascimento, Nancy R Sturm   +2 more
openaire   +1 more source

Challenges imposed by minor reference alleles on the identification and reporting of clinical variants from exome data

BMC Genomics, 2018
Background The conventional variant calling of pathogenic alleles in exome and genome sequencing requires the presence of the non-pathogenic alleles as genome references.
Mahmoud Koko, Mohammed O. E. Abdallah, Mutaz Amin, Muntaser Ibrahim   +3 more
doaj   +1 more source

Treatment-Based Strategy for the Management of Post-Kala-Azar Dermal Leishmaniasis Patients in the Sudan

Journal of Tropical Medicine, 2013
Post-kala-azar dermal leishmaniasis (PKDL) is a dermatosis that affects more than 50% of successfully treated visceral leishmaniasis (VL) patients in Sudan.
A. M. Musa, E. A. G. Khalil, B. M. Younis, M. E. E. Elfaki, M. Y. Elamin, A. O. A. Adam, H. A. A. Mohamed, M. M. M. Dafalla, A. A. Abuzaid, A. M. El-Hassan   +9 more
doaj   +1 more source

Visceral leishmaniasis-hepatitis B/C coinfections: a rising necessity to triage patients for treatment

Annals of Saudi Medicine, 2014
BACKGROUND AND OBJECTIVES: Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In Sudan, VL is caused by L donovani. Most drugs used to treat VL, especially pentavalent antimony compounds (sodium stibogluconate, SSG),
Abubakr O. A. Adam, Mohamed M. M. Dafalla, Hatim A. A. Mohammed, Mohamed Y. Elamin, Brima M. Younis, Mona E. E. Elfaki, Ahmed M. Musa, Ahmed M. Elhassan, Eltahir A. G. Khalil   +8 more
doaj   +1 more source

Endemic Disease Models [PDF]

, 2019
In this chapter, we consider models for disease that may be endemic. In the preceding chapter we studied SIS models with and without demographics and SIR models with demographics. In each model, the basic reproduction number [Formula: see text] determined a threshold. If [Formula: see text] the disease dies out, while if [Formula: see text] the disease
Brauer, Fred, Castillo-Chavez, Carlos, Feng, Zhilan   +2 more
openaire   +1 more source

Correction to: Three novel circRNAs upregulated in tissue and plasma from hepatocellular carcinoma patients and their regulatory network

Cancer Cell International, 2021
An amendment to this paper has been published and can be accessed via the original article.
Lianghai Wang, Lisha Zhou, Jun Hou, Jin Meng, Ke Lin, Xiangwei Wu, Xueling Chen   +6 more
doaj   +1 more source

Three novel circRNAs upregulated in tissue and plasma from hepatocellular carcinoma patients and their regulatory network

Cancer Cell International, 2021
Background The regulatory roles of circular RNAs (circRNAs) in tumorigenesis have attracted increasing attention. However, novel circRNAs with the potential to be used as serum/plasma biomarkers and their regulatory mechanism in the pathogenesis of ...
Lianghai Wang, Lisha Zhou, Jun Hou, Jin Meng, Ke Lin, Xiangwei Wu, Xueling Chen   +6 more
doaj   +1 more source

A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism

Molecular Brain, 2022
Psychiatric disorders and neuroticism are closely associated with central nervous system, whose proper functioning depends on efficient protein renewal. This study aims to systematically analyze the association between anxiety / depression / neuroticism ...
Bolun Cheng, Xuena Yang, Shiqiang Cheng, Chun’e Li, Huijie Zhang, Li Liu, Peilin Meng, Yumeng Jia, Yan Wen, Feng Zhang   +9 more
doaj   +1 more source

Geographical influences on the iodine status in pregnant women, neonates, and school-age children in China

Nutrition Journal, 2020
Background Pregnant women, neonates, and school-age children are vulnerable to iodine deficiency. The iodine contents in the environment (drinking water and household salt for cooking) vary by geographical location in China.
Xiaoming Lou, Xiaofeng Wang, Guangming Mao, Wenming Zhu, Zhe Mo, Yuanyang Wang, Zhifang Wang   +6 more
doaj   +1 more source

Association between gut microbiota and longevity: a genetic correlation and mendelian randomization study

BMC Microbiology, 2022
Background Longevity is one of the most complex phenotypes, and its genetic basis remains unclear. This study aimed to explore the genetic correlation and potential causal association between gut microbiota and longevity.
Dan He, Li Liu, Zhen Zhang, Xuena Yang, Yumeng Jia, Yan Wen, Shiqiang Cheng, Peilin Meng, Chun’e Li, Huijie Zhang, Chuyu Pan, Feng Zhang   +11 more
doaj   +1 more source