Results 81 to 90 of about 25,542 (192)

Cannabinoids: Well-Suited Candidates for the Treatment of Perinatal Brain Injury

Brain Sciences, 2013
Perinatal brain injury can be induced by a number of different damaging events occurring during or shortly after birth, including neonatal asphyxia, neonatal hypoxia-ischemia and stroke-induced focal ischemia.
José Martínez-Orgado, Maria Ángeles Moro, Ignacio Lizasoain, David Fernández-López   +3 more
doaj   +1 more source

Treatment of Canine Atopic Dermatitis: Updated Guidelines From the International Committee on Allergic Diseases of Animals (ICADA)

Veterinary Dermatology, EarlyView.
ABSTRACT Background Canine atopic dermatitis (cAD) is a genetically, aetiologically, immunologically and clinically complex disease requiring both individualised immediate and long‐term management. Objectives These updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA) aim to substantially revise previous ...
Ralf S. Mueller, Frane Banovic, Emmanuel Bensignor, Domenico Santoro, Tim Nuttall   +4 more
wiley   +1 more source

Alterations of the endocannabinoid system in adolescents with non-suicidal self-injury as a function of childhood maltreatment

Translational Psychiatry
Non-suicidal self-injury (NSSI) is a highly prevalent phenomenon in adolescence, often associated with prior traumatic experiences. The development and maintenance of NSSI is associated with dysregulation of the stress response, and evidence suggests ...
Marc D. Ferger, Christine Sigrist, Susanne Brodesser, Michael Kaess, Julian Koenig   +4 more
doaj   +1 more source

Lactobacillus johnsonii Improves Intestinal Barrier Function and Reduces Post-Weaning Diarrhea in Piglets: Involvement of the Endocannabinoid System

Animals
Probiotic intervention is a well-established approach for replacing antibiotics in the management of weaning piglet diarrhea, which involves a large number of complex systems interacting with the gut microbiota, including the endocannabinoid system ...
Zhangzheng Yin, Kaijun Wang, Yun Liu, Yunxia Li, Fang He, Jie Yin, Wenjie Tang   +6 more
doaj   +1 more source

Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

Neurobiology of Disease, 2015
Current concepts suggest that exposure to THC during adolescence may act as a risk factor for the development of psychiatric disorders later in life. However, the molecular underpinnings of this vulnerability are still poorly understood. To analyze this,
Tiziana Rubino, Pamela Prini, Fabiana Piscitelli, Erica Zamberletti, Massimo Trusel, Miriam Melis, Claudia Sagheddu, Alessia Ligresti, Raffaella Tonini, Vincenzo Di Marzo, Daniela Parolaro   +10 more
doaj   +1 more source

Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study

Veterinary Surgery, EarlyView.
Abstract Objective To determine short‐ and long‐term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate‐to‐severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. Study design Retrospective observational study. Animals A total of 21 client‐owned Warmblood horses with
Grigorios Maleas, Mahmoud Mageed, Kristyna Hargitaiova   +2 more
wiley   +1 more source

Research mapping of cannabinoids and endocannabinoid system in cancer over the past three decades: insights from bibliometric analysis

Frontiers in Pharmacology
BackgroundThe cannabinoids and endocannabinoid system are thought to play critical roles in multiple signaling pathways in organisms, and extensive evidence from preclinical studies indicated that cannabinoids and endocannabinoids displayed anticancer ...
Yaqian Tan, Yaqian Tan, Hui Xia, Hui Xia, Qi Song   +4 more
doaj   +1 more source

Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications

Experimental Physiology, EarlyView.
Abstract Placebo and nocebo effects on pain provide a model for investigating how cognitive and contextual factors modulate the physiological processes underlying nociception and its regulation. However, existing accounts remain fragmented and lack a unifying mechanistic framework linking brain, behaviour and autonomic responses.
Denisa Adina Zamfira, Tommaso Fassina, Kamil Zaworski, Elisa Carlino, Giacomo Rossettini   +4 more
wiley   +1 more source

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

Experimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas, Cristián A. Amador, Susana Contreras‐Duarte   +2 more
wiley   +1 more source

Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta

Mediators of Inflammation, 2015
Mammalian placentation is a vital facet of the development of a healthy and viable offspring. Throughout gestation the placenta changes to accommodate, provide for, and meet the demands of a growing fetus. Gestational gene expression is a crucial part of
Kanchan Vaswani, Hsiu-Wen Chan, Hassendrini N. Peiris, Marloes Dekker Nitert, Ryan J. Wood Bradley, James A. Armitage, Gregory E. Rice, Murray D. Mitchell   +7 more
doaj   +1 more source