Results 71 to 80 of about 24,740 (199)

Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring

Experimental Physiology, EarlyView.
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas, Cristián A. Amador, Susana Contreras‐Duarte   +2 more
wiley   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Roadmap for the expression of canonical and extended endocannabinoid system receptors and metabolic enzymes in peripheral organs of preclinical animal models

Physiological Reports
The endocannabinoid system is widely expressed throughout the body and is comprised of receptors, ligands, and enzymes that maintain metabolic, immune, and reproductive homeostasis.
J. J. Rosado‐Franco, A. L. Ellison, C. J. White, A. S. Price, C. F. Moore, R. E. Williams, L. B. Fridman, E. M. Weerts, D. W. Williams   +8 more
doaj   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Conjugated Linoleic Acid‐Enriched Fermented Dairy Modulates Microbiota and Metabolites to Alleviate MASLD: Insights From Multi‐Omics and Causal Mediation Analysis

Food Frontiers, Volume 7, Issue 5, September 2026.
In a 120‐day randomized trial, CLA‐enriched fermented dairy remodeled the gut microbiota and rewired host metabolic pathways in patients with MASLD. These changes were accompanied by reductions in ALT, total cholesterol, creatinine, and hs‐CRP, supporting a microbiota‐mediated dietary strategy for metabolic and liver health.
Fei Mi, Yanjiao Wang, Jia Xiong, Yiyuan Ma, Hongmei Pan, Jianzhong Yin, Yunmei Chai, Yao Wang, Xin Xu, Ai Zhang, Qingwen Ma, Hui Wang, Dongbai Liu, Shaoxiong Wu   +13 more
wiley   +1 more source

Involvement of the Endocannabinoid System in Ethanol-Induced Corticostriatal Synaptic Depression

Journal of Pharmacological Sciences, 2012
Ethanol is a wildly abused substance that causes various problems and damage in our society. We examined the connection between the action of ethanol and the endocannabinoid system in corticostriatal synaptic transmission by recording excitatory post ...
Hyeong Seok Cho, Seung Hyun Jeun, Qing-Zhong Li, Ki Jung Kim, Se Joon Choi, Ki-Wug Sung   +5 more
doaj   +1 more source

A Super‐Resolution Approach for Astrocyte‐Specific Molecular Imaging Reveals the Nanoscale Distribution of Monoacylglycerol Lipase, the Metabolic Node Between Endocannabinoid and Prostaglandin Signaling

Glia, Volume 74, Issue 9, September 2026.
Dual‐color STORM resolves the precise architecture and protein distributions within hippocampal astrocytes at the nanoscale. Identification of a sparse but specific MAGL pool in CA1 astrocytic processes. Astrocytic MAGL is not synapse‐associated, suggesting a synapse‐independent role.
Miklós Zöldi, István Katona
wiley   +1 more source

Quantifying Heteromer Partitioning Reveals Inflammation‐Dependent Redistribution of Microglial Adenosine A2A and Cannabinoid CB2 Receptors

Glia, Volume 74, Issue 9, September 2026.
Proinflammatory activation reorganizes microglial A2A and CB2 receptors, promoting their incorporation into stable heteromers and blocking agonist‐induced redistribution. The results reveal those heteromers as potential therapeutic targets in inflammatory contexts.
Rafael Franco, Jaume Lillo, Christian Griñán‐Ferré, Mercè Pallàs, Rafael Rivas‐Santisteban   +4 more
wiley   +1 more source

The endocannabinoid system and ophthalmic pathologies: a review of molecular mechanisms and its implications for clinical practice

Frontiers in Medicine
Within the last decade the role of the endocannabinoid system (ECS) has been a significant part of ophthalmic research, including both ocular physiology and the development of eye pathologies.
Tomasz Charytoniuk, Stanisław Półjanowski, Mateusz Michalak, Karolina Kaźmierczak, Bartłomiej Kałużny   +4 more
doaj   +1 more source

Gestation Related Gene Expression of the Endocannabinoid Pathway in Rat Placenta

Mediators of Inflammation, 2015
Mammalian placentation is a vital facet of the development of a healthy and viable offspring. Throughout gestation the placenta changes to accommodate, provide for, and meet the demands of a growing fetus. Gestational gene expression is a crucial part of
Kanchan Vaswani, Hsiu-Wen Chan, Hassendrini N. Peiris, Marloes Dekker Nitert, Ryan J. Wood Bradley, James A. Armitage, Gregory E. Rice, Murray D. Mitchell   +7 more
doaj   +1 more source