The Therapeutic Aspects of the Endocannabinoid System (ECS) for Cancer and their Development: From Nature to Laboratory. [PDF]
Curr Pharm Des, 2016 The endocannabinoid system (ECS) is a group of neuromodulatory lipids and their receptors, which are widely distributed in mammalian tissues. ECS regulates various cardiovascular, nervous, and immune system functions inside cells. In recent years, there has been a growing body of evidence for the use of synthetic and natural cannabinoids as potential ...
Khan MI +5 more
europepmc +4 more sources
PSILOCYBIN MITIGATES BEHAVIORAL DESPAIR AND COGNITIVE RECOGNITION IMPAIRMENTS BY REGULATING THE HYPOTHALAMIC- PITUITARY-ADRENAL (HPA) AXIS VIA THE BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) SIGNALING PATHWAY MEDIATED BY THE ENDOCANNABINOID SYSTEM (ECS) [PDF]
Int J NeuropsychopharmacolAbstract Background Dr. George Engel introduced the biopsychosocial model into the field of psychiatry 40 years ago, highlighting the profound connection between social environment and mental health.
Wang, *Zitong, Zhang, Yanbo, Li, Xin-Min
europepmc +2 more sources
The endocannabinoid system in the visual process
Journal of Photochemistry and Photobiology, 2023 An increasing number of articles have been published in recent years on the role of the endocannabinoid system (ECS) in different cellular processes. Here we review and discuss findings on the ECS in visual processing and present the structure of the ...
Susana J. Pasquaré +2 more
doaj +3 more sources
Overlapping pathways of migraine and the endocannabinoid system: Potential therapeutic targets [PDF]
NeurotherapeuticsMigraine is a disabling neurovascular disorder with limited therapeutic options, especially for patients unresponsive to current treatments targeting calcitonin gene-related peptide (CGRP) signaling.
Adriana Della Pietra, Andrew F. Russo
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The Endocannabinoid System in Neuropsychiatric Disorders: Mechanisms, Dysregulation and Therapeutic Potential [PDF]
BiomedicinesThe endocannabinoid system (ECS) is a fundamental regulator of brain and body homeostasis, integrating neural, immune, and stress-related signaling pathways. Dysregulation of ECS components, including cannabinoid receptors (CB1 and CB2), endocannabinoids
Timur Mušić, Tamara Lah Turnšek
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Endocannabinoid Modulation in Headache: Mechanisms, Models, and Translational Therapies [PDF]
CellsHeadache disorders, including migraine, tension-type headache, trigeminal autonomic cephalalgias, post-traumatic headache and medication overuse headache, represent a major global health burden and remain difficult to treat despite therapeutic advances ...
Jie Wen, Yumin Zhang
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Modulation of cellular redox homeostasis by the endocannabinoid system [PDF]
Open Biology, 2016 The endocannabinoid system (ECS) and reactive oxygen species (ROS) constitute two key cellular signalling systems that participate in the modulation of diverse cellular functions.
Christopher Lipina, Harinder S. Hundal
doaj +3 more sources
Immunomodulatory effect of Cannabis root extract on inflammatory cascades via endocannabinoid system regulation [PDF]
BMC Complementary Medicine and TherapiesBackground Cannabis roots have been widely used in traditional medicine, with documented references in classical texts describing their use for the treatment of various inflammatory diseases and pain.
Hye-Lin Jin +6 more
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Coordinated epigenetic dysregulation of CNR1 and FAAH genes drives endocannabinoid system dysfunction in anorexia nervosa [PDF]
Journal of Eating DisordersBackground Anorexia nervosa (AN) is a severe psychiatric disorder with limited biomarkers for diagnosis and treatment monitoring. We investigated endocannabinoid system (ECS) dysregulation in AN through integrated epigenetic and genetic analysis of ...
Federica Gilardini +7 more
doaj +2 more sources
Endocannabinoid Signaling for GABAergic-Microglia (Mis)Communication in the Brain Aging
Frontiers in Neuroscience, 2021 The aging brain seems to be characterized by neuronal loss leading to cognitive decline and progressively worsening symptoms related to neurodegeneration.
Jorge Carrera +8 more
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