Results 21 to 30 of about 25,158 (178)

Some Structural and Chemical Changes in Endocardial Endothelium of Rats in Emotional and Pain Stress Complicated by Hypercholesterolemia

open access: yesGalician Medical Journal, 2017
The objective of the research was to study the content of some neutral lipids of endocardial endothelium in rats in relation to structural changes occurring in it, in the co-existence of emotional and pain stress, as well as alimentary ...
Igor M Luchko   +4 more
doaj   +1 more source

Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis

open access: yesCell Reports, 2020
Summary: The formation of cardiac valves depends on mechanical forces exerted by blood flow. Endocardial cells lining the interior of the heart are sensitive to these stimuli and respond by rearranging into luminal cells subjected to shear stress and ...
Federica Fontana   +5 more
doaj   +1 more source

Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish

open access: yeseLife, 2022
During cardiac development, endocardial cells (EdCs) produce growth factors to promote myocardial morphogenesis and growth. In particular, EdCs produce neuregulin which is required for ventricular cardiomyocytes (CMs) to seed the multicellular ridges ...
Jialing Qi   +5 more
doaj   +1 more source

Hypoplastic Left Heart Syndrome: A New Paradigm for an Old Disease?

open access: yesJournal of Cardiovascular Development and Disease, 2019
Hypoplastic left heart syndrome occurs in up to 3% of all infants born with congenital heart disease and is a leading cause of death in this population. Although there is strong evidence for a genetic component, a specific genetic cause is only known in ...
Paul Grossfeld   +4 more
doaj   +1 more source

The effect of exercise training on left ventricular function in young elite athletes

open access: yesCardiovascular Ultrasound, 2011
Background Regular training, in particular endurance exercise, induces structural myocardial adaptation, so-called "athlete's heart". In addition to the 2D standard echo parameters, assessment of myocardial function is currently possible by deformation ...
De Luca Alessio   +4 more
doaj   +1 more source

Attenuation of stretch-induced arrhythmias following chemical ablation of Purkinje fibres, in isolated rabbit hearts

open access: yesFrontiers in Physiology, 2023
Purkinje fibres (PFs) play an important role in some ventricular arrhythmias and acute ventricular stretch can evoke mechanically-induced arrhythmias. We tested whether Purkinje fibres, play a role in these arrhythmias.
Miriam Hurley   +10 more
doaj   +1 more source

Morphofunctional Peculiarities of Endocardium of the Ventricles, Main Arteries Normally and Under the Influence of Various Factors (Literature Review)

open access: yesGalician Medical Journal, 2019
The article analyzes the data of literary sources about the histological and ultramicroscopic structure of the endocardium of the ventricles and arteries of various types and caliber normally, as well as under the influence of various endo- and exogenous
Liliya Sobol, Oksana Popadynets
doaj   +1 more source

Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion

open access: yesFrontiers in Cell and Developmental Biology, 2020
Heart regeneration requires replenishment of lost cardiomyocytes (CMs) and cells of the endocardial lining. However, the signaling regulation and transcriptional control of myocardial dedifferentiation and endocardial activation are incompletely ...
Yabo Fang   +7 more
doaj   +1 more source

Outflow Tract Formation—Embryonic Origins of Conotruncal Congenital Heart Disease

open access: yesJournal of Cardiovascular Development and Disease, 2021
Anomalies in the cardiac outflow tract (OFT) are among the most frequent congenital heart defects (CHDs). During embryogenesis, the cardiac OFT is a dynamic structure at the arterial pole of the heart.
Sonia Stefanovic   +2 more
doaj   +1 more source

Zebrafish Vestigial Like Family Member 4b Is Required for Valvulogenesis Through Sequestration of Transcription Factor Myocyte Enhancer Factor 2c

open access: yesFrontiers in Cell and Developmental Biology, 2019
A variety of cardiac transcription factors/cofactors, signaling pathways, and downstream structural genes integrate to form the regulatory hierarchies to ensure proper cardiogenesis in vertebrate.
Chang Xue   +6 more
doaj   +1 more source

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