Results 31 to 40 of about 25,313 (227)

β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos

open access: yesJournal of Biomedical Science, 2011
Background β-Lapachone has antitumor and wound healing-promoting activities. To address the potential influences of various chemicals on heart development of zebrafish embryos, we previously treated zebrafish embryos with chemicals from a Sigma LOPAC1280™
Huang Chang-Jen   +7 more
doaj   +1 more source

Strong as a Hippo’s Heart: Biomechanical Hippo Signaling During Zebrafish Cardiac Development

open access: yesFrontiers in Cell and Developmental Biology, 2021
The heart is comprised of multiple tissues that contribute to its physiological functions. During development, the growth of myocardium and endocardium is coupled and morphogenetic processes within these separate tissue layers are integrated.
Dorothee Bornhorst   +3 more
doaj   +1 more source

Some Structural and Chemical Changes in Endocardial Endothelium of Rats in Emotional and Pain Stress Complicated by Hypercholesterolemia

open access: yesGalician Medical Journal, 2017
The objective of the research was to study the content of some neutral lipids of endocardial endothelium in rats in relation to structural changes occurring in it, in the co-existence of emotional and pain stress, as well as alimentary ...
Igor M Luchko   +4 more
doaj   +1 more source

Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis

open access: yesCell Reports, 2020
Summary: The formation of cardiac valves depends on mechanical forces exerted by blood flow. Endocardial cells lining the interior of the heart are sensitive to these stimuli and respond by rearranging into luminal cells subjected to shear stress and ...
Federica Fontana   +5 more
doaj   +1 more source

Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish

open access: yeseLife, 2022
During cardiac development, endocardial cells (EdCs) produce growth factors to promote myocardial morphogenesis and growth. In particular, EdCs produce neuregulin which is required for ventricular cardiomyocytes (CMs) to seed the multicellular ridges ...
Jialing Qi   +5 more
doaj   +1 more source

The Endocardium and Heart Valves

open access: yesCold Spring Harbor Perspectives in Biology, 2020
Endocardial cells are specialized endothelial cells that, during embryogenesis, form a lining on the inside of the developing heart, which is maintained throughout life. Endocardial cells are an essential source for several lineages of the cardiovascular system including coronary endothelium, endocardial cushion mesenchyme, cardiomyocytes, mural cells,
Bailey, Dye, Joy, Lincoln
openaire   +3 more sources

Attenuation of stretch-induced arrhythmias following chemical ablation of Purkinje fibres, in isolated rabbit hearts

open access: yesFrontiers in Physiology, 2023
Purkinje fibres (PFs) play an important role in some ventricular arrhythmias and acute ventricular stretch can evoke mechanically-induced arrhythmias. We tested whether Purkinje fibres, play a role in these arrhythmias.
Miriam Hurley   +10 more
doaj   +1 more source

Hypoplastic Left Heart Syndrome: A New Paradigm for an Old Disease?

open access: yesJournal of Cardiovascular Development and Disease, 2019
Hypoplastic left heart syndrome occurs in up to 3% of all infants born with congenital heart disease and is a leading cause of death in this population. Although there is strong evidence for a genetic component, a specific genetic cause is only known in ...
Paul Grossfeld   +4 more
doaj   +1 more source

The effect of exercise training on left ventricular function in young elite athletes

open access: yesCardiovascular Ultrasound, 2011
Background Regular training, in particular endurance exercise, induces structural myocardial adaptation, so-called "athlete's heart". In addition to the 2D standard echo parameters, assessment of myocardial function is currently possible by deformation ...
De Luca Alessio   +4 more
doaj   +1 more source

Tbx20 Induction Promotes Zebrafish Heart Regeneration by Inducing Cardiomyocyte Dedifferentiation and Endocardial Expansion

open access: yesFrontiers in Cell and Developmental Biology, 2020
Heart regeneration requires replenishment of lost cardiomyocytes (CMs) and cells of the endocardial lining. However, the signaling regulation and transcriptional control of myocardial dedifferentiation and endocardial activation are incompletely ...
Yabo Fang   +7 more
doaj   +1 more source

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