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Effects of endocrine disrupting chemicals in pigs
Environmental Pollution, 2020Endocrine-disrupting chemicals (EDCs) are compounds that interfere with the expression, synthesis, and activity of hormones in organisms. They are released into the environment from flame retardants and products containing plasticizers. Persistent pesticides, such as dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene, also disrupt the ...
Changwon, Yang +2 more
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Endocrine-disrupting chemicals and child health
Best Practice & Research Clinical Endocrinology & Metabolism, 2021Endocrine-disrupting chemicals (EDCs) are chemicals which are introduced into the environment by human activities. In many cases it has been proven that EDCs can cause adverse health effects in the human. EDCs are classified by their chemical structure, putative direct or indirect effects on endocrine glands and systems, may accumulate and persist in ...
Wieland, Kiess +2 more
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Anthropogenic tracers, endocrine disrupting chemicals, and endocrine disruption in Minnesota lakes
Science of The Total Environment, 2010Concentrations of endocrine disrupting chemicals and endocrine disruption in fish were determined in 11 lakes across Minnesota that represent a range of trophic conditions and land uses (urban, agricultural, residential, and forested) and in which wastewater treatment plant discharges were absent.
Jeffrey H, Writer +8 more
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Endocrine-Disrupting Chemicals
JAMA, 20131Zeneca, Macclesfield, Cheshire, United Kingdom; 2Akzo Nobel Chemicals, Amersfoort, The Netherlands; 3Unilever, Bedford, UK; 4Ciba-Geigy, Basel, Switzerland; 5Rh6ne-Poulenc Agro, Sophia Antipolis, France; 6Bayer Ag, Wuppertal, Germany; 7Procter & Gamble, Strombeek-Bever, Belgium; 8Union Carbide Corporation, Danbury, CT 06817-0001 USA; 9European Centre ...
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The effects of endocrine disrupting chemicals on the ovary
Frontiers in Bioscience, 2002Endocrine disrupting chemicals (EDCs) are natural or synthetic chemicals that mimic, enhance, or inhibit endogenous hormones. In this article, we review possible targets of EDCs within the ovary and explore whether EDCs may be acting as estrogen mimics, interfering with apoptosis, altering cell signaling pathways, or affecting estrogen metabolism ...
C, Borgeest +3 more
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Endocrine Disrupting Chemicals
1999Long-term environmental effects of chemical exposure have long been of concern and, more recently, chemicals which cause changes to the sexual development of exposed organisms have been identified. It is thought that low-level exposure to a wide range of chemicals may be affecting endocrine function, leading to a reduction in fertility and an increase ...
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Endocrine disrupting chemicals and growth of children
Annales d'Endocrinologie, 2017According to the "environmental obesogen hypothesis", early-life (including in utero) exposure to endocrine disrupting chemicals (EDCs) may disturb the mechanisms involved in adipogenesis or energy storage, and thus may increase the susceptibility to overweight and obesity.
Botton, Jérémie +2 more
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Endocrine disrupting chemicals
The Journal of Steroid Biochemistry and Molecular Biology, 2011Blumberg, Bruce +2 more
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Endocrine disrupting chemicals and the mammary gland
2021Development of the mammary gland requires coordination of hormone signaling pathways including those mediated by estrogen, progesterone, androgen and prolactin receptors. These hormones play important roles at several distinct stages of life including embryonic/fetal development, puberty, pregnancy, lactation, and old age.
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Toxicity testing and endocrine disrupting chemicals
2021Regulatory agencies around the world depend on standardized testing approaches to evaluate environmental chemicals for endocrine disrupting properties. The US Environmental Protection Agency (EPA) has developed a two-tiered testing approach within its Endocrine Disruptor Screening Program (EDSP).
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