Results 31 to 40 of about 21,695 (255)

Invited Lecture 2: Endocrine disrupting chemicals in ocean ecosystem and human health risks

BLDE University Journal of Health Sciences, 2020
Brief Biosketch He is the author of 5 books and edited 7 books (chapters). He has published peer-reviewed articles in several reputed journals. He is serving as a Course Coordinator for Undergraduate (MD) teaching: Environmental health.
Atanu Sarkar
doaj   +1 more source

Endocrine Disrupting Chemicals and Thyroid Cancer: An Overview

Toxics, 2021
Endocrine disruptive chemicals (EDC) are known to alter thyroid function and have been associated with increased risk of certain cancers. The present study aims to provide a comprehensive overview of available studies on the association between EDC ...
Mathilda Alsen, Catherine Sinclair, Peter Cooke, Kimia Ziadkhanpour, Eric Genden, Maaike van Gerwen   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Immunomodulatory effects of environmental endocrine disrupting chemicals

Kaohsiung Journal of Medical Sciences, 2012
During recent decades more than 100,000 new chemicals have been introduced as common consumer products into our environment. Among these chemicals, endocrine-disrupting chemicals (EDCs) are of particular concern owing to their toxicity in animal studies ...
Chang-Hung Kuo, San-Nan Yang, Po-Lin Kuo, Chih-Hsing Hung   +3 more
doaj   +1 more source

Development of new approach methods for the identification and characterization of endocrine metabolic disruptors—a PARC project

Frontiers in Toxicology, 2023
In past times, the analysis of endocrine disrupting properties of chemicals has mainly been focused on (anti-)estrogenic or (anti-)androgenic properties, as well as on aspects of steroidogenesis and the modulation of thyroid signaling.
Albert Braeuning, Patrick Balaguer, William Bourguet, Jordi Carreras-Puigvert, Katreece Feiertag, Jorke H. Kamstra, Dries Knapen, Dajana Lichtenstein, Philip Marx-Stoelting, Jonne Rietdijk, Kristin Schubert, Ola Spjuth, Evelyn Stinckens, Kathrin Thedieck, Rik van den Boom, Lucia Vergauwen, Martin von Bergen, Neele Wewer, Daniel Zalko   +18 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Role of Obesogens in the Pathogenesis of Obesity

Medicina, 2019
Obesity is considered to be a 20th century pandemic, and its prevalence correlates with the increasing global pollution and the presence of chemical compounds in the environment.
Urszula Shahnazaryan, Marta Wójcik, Tomasz Bednarczuk, Alina Kuryłowicz   +3 more
doaj   +1 more source

Combined toxicity of endocrine-disrupting chemicals: A review

Ecotoxicology and Environmental Safety, 2021
The combined toxicological assessment provides a realistic approach for hazard evaluation of chemical cocktails that co-existed in the environment.
Naima Hamid, Muhammad Junaid, De-Sheng Pei   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source