Results 41 to 50 of about 55,055 (299)

Combined toxicity of endocrine-disrupting chemicals: A review

open access: yesEcotoxicology and Environmental Safety, 2021
The combined toxicological assessment provides a realistic approach for hazard evaluation of chemical cocktails that co-existed in the environment.
Naima Hamid   +2 more
doaj   +1 more source

Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Obesity

open access: yesBiomedicines, 2021
The incidence of obesity has dramatically increased over the last decades. Recently, there has been a growing interest in the possible association between the pandemics of obesity and some endocrine-disrupting chemicals (EDCs), termed “obesogens”.
Immacolata Cristina Nettore   +4 more
doaj   +1 more source

Endocrine disrupting effects on the nesting behaviour of male three-spined stickleback Gasterosteus aculeatus L [PDF]

open access: yes, 2006
The analysis of patterns of temporal variability in the nesting behaviour of male threespined stickleback (Gasterosteus aculeatus) exposed to the synthetic oestrogen, 17β-ethinylestradiol, revealed immediate, but transient, treatment-related effects ...
Borg B.   +4 more
core   +1 more source

Role of Obesogens in the Pathogenesis of Obesity

open access: yesMedicina, 2019
Obesity is considered to be a 20th century pandemic, and its prevalence correlates with the increasing global pollution and the presence of chemical compounds in the environment.
Urszula Shahnazaryan   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Sex-change chemicals and their influence on the brain. [PDF]

open access: yes, 2001
The potential for man-made chemicals to mimic or antagonise natural hormones is a controversial issue, but one for which increasing amounts of evidence are being gathered worldwide.
Harris, CA
core   +3 more sources

Endocrine-Disrupting Chemicals and Disease Endpoints

open access: yesInternational Journal of Molecular Sciences, 2023
Endocrine-disrupting chemicals (EDCs) have significant impacts on biological systems, and have been shown to interfere with physiological systems, especially by disrupting the hormone balance. During the last few decades, EDCs have been shown to affect reproductive, neurological, and metabolic development and function and even stimulate tumor growth ...
Changhwan Ahn, Eui-Bae Jeung
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Influence of Endogenous and Exogenous Estrogenic Endocrine on Intestinal Microbiota in Zebrafish.

open access: yesPLoS ONE, 2016
Gender is one of the factors influencing the intestinal microbial composition in mammals, but whether fish also have gender-specific intestinal microbial patterns remains unknown. In this decade, endocrine disrupting chemicals in surface and ground water
Yukun Liu   +6 more
doaj   +1 more source

Endocrine-Disrupting Chemicals: Testing to Protect Future Generations [PDF]

open access: yes, 2011
Endocrine-disrupting chemicals (EDCs) are a class of chemicals that interferes with human hormone processes. EDCs are omnipresent: pesticides, plastics, and drugs, among other common chemicals, all demonstrate endocrine-disrupting properties.
Van der Mude, Alana
core  

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