Neural cell adhesion molecules in rat endocrine tissues and tumor cells: distribution and molecular analysis [PDF]
, 1993 The adhesive properties of neural cell adhesion molecules (NCAMs) can be modified by alternative splicing of the primary transcript or posttranslational modifications.
Barthels, D. +5 more
core +1 more source
Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells
FEBS Open Bio, 2023 Wolfram syndrome is a monogenic disease mainly caused by mutations in the WFS1 gene. Mutations in the WFS1 gene give rise to diabetes. Here, we characterized mutant WFS1 proteins by studying the stability of full‐length wild‐type (WT) WFS1, a missense ...
Hiraku Tokuma +5 more
doaj +1 more source
Pituitary Pars Intermedia Dysfunction (PPID) in Horses
Veterinary Sciences, 2022 Substantial morbidity results from pituitary pars intermedia dysfunction (PPID) which is often underestimated by owners and veterinarians. Clinical signs, pathophysiology, diagnostic tests, and treatment protocols of this condition are reviewed.
Naomi C. Kirkwood +2 more
doaj +1 more source
Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]
, 2015 The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella +7 more
core +1 more source
Morphometric Analysis of Fetal Pancreas
MRIMS Journal of Health Sciences, 2016 Background: Pancreas is an important organ and it is the target of major diseases like pancreatitis, diabetes mellitus, exocrine pancreatic insufficiency, cystic fibrosis, pseudo-cysts, annular pancreas, neoplasm etc.
B Immanuel Navin Kumar +4 more
doaj +1 more source
Frontiers in Endocrinology, 2023 IntroductionNear infrared autofluorescence (NIRAF) is a novel intraoperative technology that has shown promising results in the localisation of parathyroid glands (PGs) over the last decade.
Arslan Y. Pannu +5 more
doaj +1 more source
Endocrine Disrupting Chemicals: Effects on Endocrine Glands [PDF]
Frontiers in Endocrinology, 2019 In recent years, endocrine disrupting chemicals have gained interest in human physiopathology and more and more studies aimed to explain how these chemicals compounds affect endocrine system. In human populations, the majority of the studies point toward an association between exposure to endocrine disrupting chemicals and the disorders affecting ...
Lauretta R. +4 more
openaire +5 more sources
Future Science OA, 2021 Aim: The hypothalamic–pituitary–adrenal axis is involved in maintaining homeostasis by engaging with the parasympathetic nervous system. During the process of disease affliction, this relationship is disturbed and there is an imbalance driven response ...
Sayali Upasham +3 more
doaj +1 more source
Using zebrafish (Danio rerio) to study the behavioral impacts of early bisphenol F exposure reveals decreased swim speed, increased distance between fish, and increased freezing behaviors [PDF]
, 2020 The widespread use of endocrine disrupting chemicals (EDCs) has been a source of concern because of their various effects on the endocrine system. These effects include metabolic disorders, complications in reproductive health, hormone-related cancers ...
Conner, Meghan, Freeman, Edward A.
core +1 more source
DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation [PDF]
, 2015 The acquisition of endocrine therapy resistance in estrogen receptor a (ERa) breast cancer patients represents a major clinical problem. Notch signalling has been extensively linked to breast cancer especially in patients who fail to respond to endocrine
Aifantis +54 more
core +3 more sources