Results 1 to 10 of about 173,464 (288)

Prenatal exposure to phenols and benzophenones in relation to markers of male reproductive function in adulthood

Frontiers in Endocrinology, 2022
IntroductionEnvironmental exposure during fetal life may disrupt testicular development. In humans, a limited number of studies have investigated whether these adverse effects persist into adulthood.
Stine A. Holmboe, Stine A. Holmboe, Louise Scheutz Henriksen, Louise Scheutz Henriksen, Hanne Frederiksen, Hanne Frederiksen, Anna-Maria Andersson, Anna-Maria Andersson, Lærke Priskorn, Lærke Priskorn, Niels Jørgensen, Niels Jørgensen, Anders Juul, Anders Juul, Anders Juul, Jorma Toppari, Jorma Toppari, Jorma Toppari, Niels E. Skakkebæk, Niels E. Skakkebæk, Niels E. Skakkebæk, Katharina M. Main, Katharina M. Main, Katharina M. Main   +23 more
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Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism

Frontiers in Endocrinology, 2021
ObjectiveInsulin-like factor 3 (INSL3) is produced in the testes and has been proposed as a circulating biomarker of Leydig cell capacity, but remains undescribed in 45,X/46,XY mosaicism. The aim was to examine serum concentrations and gonadal expression
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Anne Jørgensen, Anne Jørgensen, Lise Aksglaede, Lise Aksglaede, John Erik Nielsen, John Erik Nielsen, Jakob Albrethsen, Jakob Albrethsen, Anders Juul, Anders Juul, Trine Holm Johannsen, Trine Holm Johannsen   +13 more
doaj   +1 more source

Serum LH/FSH ratios in 87 infants with differences of sex development

Endocrine Connections, 2023
The ratio between luteinizing hormone (LH) and follicle-stimulating hormone (FSH) has previously been described as an excellent marker of sex in healthy infants. However, LH/ FSH remains not fully described in patients with differences of sex development
Marie Lindhardt Ljubicic, Trine Holm Johannsen, Margit Bistrup Fischer, Emmie N Upners, Alexander S Busch, Katharina M Main, Anna-Maria Andersson, Casper P Hagen, Anders Juul   +8 more
doaj   +1 more source

Longitudinal evaluation of breast tissue in healthy infants: Prevalence and relation to reproductive hormones and growth factors

Frontiers in Endocrinology, 2022
IntroductionBreast tissue in infancy is a rather undescribed phenomenon. We aimed to describe the prevalence and progression of palpable breast tissue in healthy boys and girls aged 0-1 years and to evaluate clinical markers, individual serum hormone ...
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Andre Madsen, Emmie N. Upners, Emmie N. Upners, Margit Bistrup Fischer, Margit Bistrup Fischer, Alexander Siegfried Busch, Alexander Siegfried Busch, Alexander Siegfried Busch, Hanne Frederiksen, Hanne Frederiksen, Trine Holm Johannsen, Trine Holm Johannsen, Anders Juul, Anders Juul, Anders Juul, Casper P. Hagen, Casper P. Hagen   +18 more
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The Application of Principal Component Analysis on Clinical and Biochemical Parameters Exemplified in Children With Congenital Adrenal Hyperplasia

Frontiers in Endocrinology, 2021
PurposePrincipal component analysis (PCA) is a mathematical model which simplifies data into new, combined variables. Optimal treatment of pediatric congenital adrenal hyperplasia (CAH) remains a challenge and requires evaluation of all biochemical and ...
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Andre Madsen, Andre Madsen, Andre Madsen, Anders Juul, Anders Juul, Kristian Almstrup, Kristian Almstrup, Trine Holm Johannsen, Trine Holm Johannsen   +10 more
doaj   +1 more source

Non-Classic Congenital Adrenal Hyperplasia in Two Adolescents With Gender Dysphoria

Journal of Psychosexual Health, 2021
The care of transgender individuals is multidisciplinary including medical, surgical, psychiatric, and psychological health professionals. We here report 2 cases of nonclassic congenital adrenal hyperplasia (CAH) coincidently discovered during the ...
Emma Wall, Lise Aksglaede, Mette Ewers Haahr, Peter Christiansen, Katharina M. Main   +4 more
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In vitro investigation of endocrine disrupting effects of pesticides on Ca2+-signaling in human sperm cells through actions on the sperm-specific and steroid-activated CatSper Ca2+-channel

Environment International, 2022
Background: Ca2+-signaling controls sperm cell functions necessary for successful fertilization. Multiple endocrine disrupting chemicals have been found to interfere with normal Ca2+-signaling in human sperm cells through an activation of the sperm ...
Michala R. Birch, Mathias Johansen, Niels E. Skakkebæk, Anna-Maria Andersson, Anders Rehfeld   +4 more
doaj   +1 more source

Levels of endocrine-disrupting chemicals are associated with changes in the peri-pubertal epigenome

Endocrine Connections, 2020
Puberty marks a transition period, which leads to the attainment of adult sexual maturity. Timing of puberty is a strongly heritable trait. However, large genetic association studies can only explain a fraction of the observed variability and striking ...
Kristian Almstrup, Hanne Frederiksen, Anna-Maria Andersson, Anders Juul   +3 more
doaj   +1 more source

Exposure to 15 phthalates and two substitutes (DEHTP and DINCH) assessed in trios of infants and their parents as well as longitudinally in infants exclusively breastfed and after the introduction of a mixed diet

Environment International, 2022
Objective: Several phthalates have been restricted/banned due to their adverse endocrine disrupting properties. The use of other phthalates and substitutes has increased.
Hanne Frederiksen, Emmie N. Upners, Marie Lindhardt Ljubicic, Margit Bistrup Fischer, Alexander Siegfried Busch, Casper P. Hagen, Anders Juul, Anna-Maria Andersson   +7 more
doaj   +1 more source

AMH and other markers of ovarian function in patients with Turner syndrome – a single center experience of transition from pediatric to gynecological follow up

Frontiers in Endocrinology, 2023
Turner syndrome (TS) is a chromosomal disorder that affects about 1 in 2500 female births and is characterized by the partial or complete absence of the second X chromosome. Depending on karyotype, TS is associated with primary ovarian insufficiency (POI)
Casper P. Hagen, Casper P. Hagen, Margit Bistrup Fischer, Margit Bistrup Fischer, Gylli Mola, Gylli Mola, Theis Bech Mikkelsen, Theis Bech Mikkelsen, Line Hartvig Cleemann, Line Hartvig Cleemann, Claus Højbjerg Gravholt, Claus Højbjerg Gravholt, Mette H. Viuff, Anders Juul, Anders Juul, Anders Juul, Anette Tønnes Pedersen, Katharina Maria Main, Katharina Maria Main, Katharina Maria Main   +19 more
doaj   +1 more source