Results 91 to 100 of about 1,334,386 (213)

Thyroid endocrine disruption in zebrafish larvae following exposure to hexaconazole and tebuconazole.

Aquatic Toxicology, 2013
The widely used triazole fungicides have the potential to disrupt endocrine system, but little is known of such effects or underlying mechanisms of hexaconazole (HEX) and tebuconazole (TEB) in fish.
Liang Yu, Mengli Chen, Yihua Liu, Wenjun Gui, Guonian Zhu   +4 more
semanticscholar   +1 more source

Tissue‐Stimulator Platform for Electrically Stimulating Pancreatic β‐Cells for Long‐Term Functional Regulation

Advanced Functional Materials, EarlyView.
We present a tissue‐stimulator platform for seamless electrode integration with pancreatic tissue, applying uniform electrical stimulation through optimized design with biohybrid 3D printing. Advantageous effects of electrical stimulation on β‐cell function were observed, including enhanced calcium signaling, islet morphology, and maturation.
Jihwan Kim, Uijung Yong, Myungji Kim, Jaewook Kim, Yeonggwon Jo, In Kyong Shim, Song Cheol Kim, Jinah Jang   +7 more
wiley   +1 more source

The Impact of Endocrine Disruption: A Consensus Statement on the State of the Science

Environmental Health Perspectives, 2013
Perspectives | Editorial The Impact of Endocrine Disruption: A Consensus Statement on the State of the Science doi:10.1289/ehp.1205448 Ake Bergman, 1 Jerrold J. Heindel, 2,a Tim Kasten, 3,b Karen A. Kidd, 4 Susan Jobling, 5 Maria Neira, 6,c R.
A. Bergman, J. Heindel, Tim Kasten, Karen A. Kidd, S. Jobling, María Neira, R. Zoeller, G. Becher, P. Bjerregaard, R. Bornman, Ingvar Brandt, Andreas Kortenkamp, D. Muir, Marie Noel Brune Drisse, R. Ochieng, N. E. Skakkebaek, Agneta Sundén Byléhn, T. Iguchi, J. Toppari, Tracey J. Woodruff   +19 more
semanticscholar   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Exposure to per- and polyfluoroalkyl substances during fetal development and risk of testicular germ cell cancer in adulthood

Environment International
Background: Testicular germ cell cancer (TGCC) originates during fetal life. Fetal exposure to environmental chemicals may contribute to its development, but epidemiological data are lacking.
Cecilie S. Uldbjerg, Youn-Hee Lim, Astrid L. Beck, Jørgen H. Petersen, Karina M. Sørensen, David M. Kristensen, Panu Rantakokko, Brent A. Coull, Christian Lindh, Niels E. Skakkebæk, Russ Hauser, Elvira V. Bräuner, Lærke Priskorn, Anders Juul   +13 more
doaj   +1 more source

Imposex in Plicopurpura pansa (Neogastropoda: Thaididae) in Nayarit and Sinaloa, Mexico

Revista Mexicana de Biodiversidad, 2015
Imposex is the development of male features in female prosobranch gastropods, caused by organotin compounds. In the Mexican Pacific coast, imposex was observed in Plicopurpura pansa.
Delia Domínguez-Ojeda, Olga Araceli Patrón-Soberano, José Trinidad Nieto-Navarro, María de Lourdes Robledo-Marenco, Jesús Bernardino Velázquez-Fernández   +4 more
doaj   +1 more source

A Long‐Lived Human Neurovascular PENTA Culture Model Captures Incomplete Vascular Repair and Glia‐Associated Signaling After Traumatic Brain Injury

Advanced Healthcare Materials, EarlyView.
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen, Sunghyun Jun, Colleen M. Arrasmith, Charitha C. Anamala, Mitchell D. Thielen, Anapaula Garcia, Volha Liaudanskaya   +6 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

Advanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima, Sarmila Majumder, Divya S. Patel, Chunyu Hu, Hong Li, Xin Huang, Kim Truc Nguyen, Jacob Doon‐Ralls, Chiranth K. Nagaraj, Mangesh D. Hade, Setty M. Magaña, Eswar Shankar, Xiaoli Zhang, Daniel G. Stover, Bhuvaneswari Ramaswamy, Eduardo Reátegui   +15 more
wiley   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Integrated Visible Light and Oxidant Protection Through Multifunctional Sunscreens

Advanced Healthcare Materials, EarlyView.
High‐energy visible radiation (HEVR), although less energetic than UV light, penetrates deeper into the skin and contributes to photoaging, pigmentation disorders, and oxidative stress. The development of new HEVR‐targeted filters, therefore, represents not only a scientific challenge but also a pressing public health and cosmetic industry need.
Beatriz Peñín, Raúl Losantos, Ignacio Funes‐Ardoiz, Diego Sampedro   +3 more
wiley   +1 more source