Results 1 to 10 of about 2,190 (162)

Insulin-like peptide 3 is not a biomarker for pancreatic ductal adenocarcinoma [PDF]

Frontiers in Endocrinology
Pancreatic ductal carcinoma (PDAC) is a rapidly growing cancer with a very poor prognosis. It is, therefore, important to develop novel, specific biomarkers to identify such cancers as early as possible.
Ravinder Anand-Ivell, Xinyuan Yang, Ruediger Braun, Hendrik Ungefroren, Richard Ivell, Richard Ivell   +5 more
doaj   +2 more sources

Potential ability of circulating INSL3 level for the prediction of ovarian reserve and IVF success as a novel theca cell–specific biomarker in women with unexplained infertility and diminished ovarian reserve [PDF]

Reproductive Biology and Endocrinology
Background Insulin-like peptide (INSL3), belonging to the insulin-like peptide family, is produced by theca interna cells within antral follicles and the corpora lutea.
Pinar Ozcan, F. Sezer, A. Altun, C. Yildiz, H. T. Timur, E. C. Keles, O. Dural, H. S. Taha, E. Saridogan   +8 more
doaj   +2 more sources

Evolutionary relaxation and functional change of INSL3 and RXFP2 may underlie natural cryptorchidism in mammals [PDF]

EMBO Reports
Cryptorchidism is a common congenital abnormality that increases infertility and testicular cancer risk in adulthood. However, a few mammals exhibit naturally undescended testes while maintaining normal reproduction.
Yu Zheng, Simin Chai, Cuijuan Zhong, Yixuan Sun, Shixia Xu, Wenhua Ren, Guang Yang   +6 more
doaj   +2 more sources

Effects of INSL3 and WNT2B gene polymorphisms on seasonal reproductive traits of Xinjiang Qira black sheep, Kazakh sheep and Duolang sheep [PDF]

Animal Biotechnology
The purpose of this study was to investigate the polymorphism and genetic correlation of INSL3 and WNT2B genes with seasonal estrus and litter size in three different Xinjiang sheep breeds.
Jingdong Bi, Sulaiman Yiming, Jiaqi Li, Quanfeng Wang, Manjun Zhai, Shaoqi Cao, Mengting Zhu, Hua Yang   +7 more
doaj   +2 more sources

Defining the end of puberty in boys: INSL3 and the acute determinants of adult Leydig-cell functional capacity [PDF]

Frontiers in Endocrinology
IntroductionTesticular Leydig cells are responsible for producing almost all the testosterone required by men throughout the lifespan, with reduced testosterone (hypogonadism) correlating with age-linked morbidity and mortality.
Bilal Tulumcu, Richard Ivell, Waleed Alhujaili, Ravinder Anand-Ivell   +3 more
doaj   +2 more sources

Spermatic RXFP2 expression levels and seminal INSL3 concentrations among beef bull ejaculates with different levels of sperm morphological normality [PDF]

The Journal of Reproduction and Development
The objective of this study was to examine the relationship between the insulin-like peptide 3 (INSL3) receptor (RXFP2) expression levels on spermatozoa and INSL3 concentrations in the seminal plasma of fresh semen from beef bulls with different levels ...
Hewage Dilhan Anuradha WIMALARATHNE, Kenta ARASHI, Fumiyuki IWAKI, Mitsuhiro SAKASE, DURITAHALA, Hiroshi HARAYAMA, Noritoshi KAWATE   +6 more
doaj   +2 more sources

Serum Concentrations and Gonadal Expression of INSL3 in Eighteen Males With 45,X/46,XY Mosaicism

Frontiers in Endocrinology, 2021
ObjectiveInsulin-like factor 3 (INSL3) is produced in the testes and has been proposed as a circulating biomarker of Leydig cell capacity, but remains undescribed in 45,X/46,XY mosaicism. The aim was to examine serum concentrations and gonadal expression
Marie Lindhardt Ljubicic, Marie Lindhardt Ljubicic, Anne Jørgensen, Anne Jørgensen, Lise Aksglaede, Lise Aksglaede, John Erik Nielsen, John Erik Nielsen, Jakob Albrethsen, Jakob Albrethsen, Anders Juul, Anders Juul, Trine Holm Johannsen, Trine Holm Johannsen   +13 more
doaj   +1 more source

Analysis of reproductive hormones and morphometric attributes in Thamankaduwa White male cattle

Cluj Veterinary Journal, 2023
Despite a few attempts in exploring genetic variability, management systems, and morphometric descriptions, Thamankaduwa White cattle in Sri Lanka has not been subjected to any evaluation of their endocrinological distinctiveness, especially related to ...
Siriwardana Tharinda Dhilshan De Silva, Oshan Bimsara Gunawardena, Mylvaganam Pagthinathan, Pradeepa Silva, Indunil Pathirana   +4 more
doaj   +3 more sources

Insulin‐like peptide 3 in domestic animals with normal and abnormal reproductive functions, in comparison to rodents and humans

Reproductive Medicine and Biology, 2022
Background Insulin‐like peptide 3 (INSL3) is a circulating hormone secreted from only testis and ovaries in mammals. Findings on INSL3 have been gathered from subjects with normal and abnormal reproductive statuses, especially rodents and humans. However,
Noritoshi Kawate
doaj   +1 more source

Quantitative analyses of insulin-like peptide 3 and sex steroid hormones in dominant follicles and corpora lutea during the estrus cycle and in follicular cysts in beef heifers

The Journal of Reproduction and Development, 2022
Insulin-like peptide 3 (INSL3) and sex steroids were measured in bovine dominant follicles and corpora lutea during the estrus cycle and in follicular cysts.
Hewage Dilhan Anuradha WIMALARATHNE, Hiroaki WAKO, Noritoshi KAWATE   +2 more
doaj   +1 more source