Results 161 to 170 of about 174,481 (308)

A Silent Threat: Exploring the Impact of Endocrine Disruption on Human Health. [PDF]

Int J Mol Sci, 2023
Leung YK.
europepmc   +1 more source

Effects of 17a-ethinyl estradiol exposure on estrogen receptors a and ß and vitellogenins A, B and C mRNA expression in the liver of sand goby (Pomatoschistus minutus) [PDF]

, 2014
Craft, John, Humble, Joseph, Lehtonen, Kari, Lindstrom, Kai, Saaristo, Minna   +4 more
core   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu, Mengqin Yuan, Yini Shang, Jiahao Chen, Fei Hou, Lihong Wang, Wei Jiang   +6 more
wiley   +1 more source

Novel mechanisms of atrazine endocrine disruption: an integrated approach reveals progesterone and glucocorticoid receptor targeting. [PDF]

BMC Pharmacol Toxicol
Jin C, Hao R, Ren X, Shen J.
europepmc   +1 more source

Editorial: Endocrine disruption in marine invertebrates. [PDF]

Front Endocrinol (Lausanne), 2022
Fernandez MA.
europepmc   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

New approach methodologies (NAMs) for improved developmental and reproductive toxicity (DART) assessment with focus on endocrine disruption - a PARC project. [PDF]

Front Toxicol
Ardenkjær-Skinnerup J, Baert Y, Bajard L, Blum J, Brion F, Coppola L, Fini JB, Fritsche E, Holbech H, Hurem S, Jacobs MN, Johansson HKL, Knapen D, Koch K, Lyche JL, Mai PNT, Neuhaus W, Nikolov NG, Nurani A, Papageorgiou K, Poulsen R, Ramhøj L, Řehůřková E, Rosenmai AK, Rüegg J, Sovadinová I, Tait S, Van de Pette M, Vanhaecke T, Vergauwen L, Wedebye EB, Xu EG, Svingen T.   +32 more
europepmc   +1 more source

The Potential for Genotoxicity, Mutagenicity and Endocrine Disruption in Triclosan and Triclocarban Assessed through a Combination of In Vitro Methods. [PDF]

J Xenobiot, 2023
Chrz J, Dvořáková M, Kejlová K, Očadlíková D, Svobodová L, Malina L, Hošíková B, Jírová D, Bendová H, Kolářová H.   +9 more
europepmc   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Endocrine Disruption as a Mediator of Declining Semen Quality in Smokers. [PDF]

Cells
Choudhury BP, Das S, Kar KK, Slama P, Kolesarova A, Rosas IM, Roychoudhury S.   +6 more
europepmc   +1 more source