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Endocrine-disrupting chemicals
Current Biology, 2022In this Quick guide, Bertram et al. discuss the environmental sources of endocrine-disrupting chemicals and their effects on biological systems.
Michael G, Bertram +3 more
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Anthropogenic tracers, endocrine disrupting chemicals, and endocrine disruption in Minnesota lakes
Science of the Total Environment, 2010Concentrations of endocrine disrupting chemicals and endocrine disruption in fish were determined in 11 lakes across Minnesota that represent a range of trophic conditions and land uses (urban, agricultural, residential, and forested) and in which wastewater treatment plant discharges were absent.
Heiko L. Schoenfuss +2 more
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Journal of Pediatric Endocrinology and Metabolism, 2005
Man does not come into the world pre-determined. The lifetime set of environmental conditions impinging on a given individual has been termed the ambiome, which together with the genome and the proteome determines each individual's development and construction. Among the most important elements making up the ambiome are endocrine disruptors.
M, Pombo, L, Castro-Feijóo
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Man does not come into the world pre-determined. The lifetime set of environmental conditions impinging on a given individual has been termed the ambiome, which together with the genome and the proteome determines each individual's development and construction. Among the most important elements making up the ambiome are endocrine disruptors.
M, Pombo, L, Castro-Feijóo
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Environmental Endocrine Disrupters
Sexual Development, 2008Androgens, anti-Müllerian hormone, and insulin-like factor 3 are testis-derived hormones that regulate male sexual differentiation. Correct timing of secretion and action of these hormones is critical for normal development. Endocrine disrupters are exogenous substances that cause adverse effects in the endocrine system.
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Adrenocortical endocrine disruption
The Journal of Steroid Biochemistry and Molecular Biology, 2016The adrenal has been neglected in endocrine disruption regulatory testing strategy. The adrenal is a vital organ, adrenocortical insufficiency is recognised in life threatening "adrenal crises" and Addison's disease, and the consequences of off-target toxicological inhibition of adrenocortical steroidogenesis is well recognised in clinical medicine ...
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Endocrine Disruption and Hypospadias
2004The complexity of human biology makes it impossible to know for certain if endocrine disruption accounts for human penile deformities. Toxicologists point out that an overall assessment of risk must include other factors in addition to exposure including absorption, metabolism, excretion, bioaccumulation and other chemical interactions (Harrison et al.,
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Endocrine disrupting chemicals and bone
Best Practice & Research Clinical Endocrinology & Metabolism, 2021Endocrine-disrupting chemicals (EDCs) are defined as chemicals that interfere with the function of the endocrine system. EDCs exert their hormonal effects through several mechanisms; modulating hormone receptors or changing metabolism of different hormones.
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Endocrine Disruption in Aquatic Vertebrates
Annals of the New York Academy of Sciences, 2009Environmental compounds can interfere with endocrine systems of wildlife and humans. The main sink of such substances, called endocrine disrupters (ED), are surface waters. Thus, aquatic vertebrates, such as fish and amphibians, are most endangered. ED can adversely affect reproductive biology and the thyroid system.
Kloas, Werner +15 more
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Endocrine disrupters: A human risk?
Molecular and Cellular Endocrinology, 2005Endocrine disrupters (EDs) alter normal hormonal regulation and may be naturally occurring or environmental contaminants. Classically, EDs act genomically, with agonistic or antagonistic effects on steroid receptors and may alter reproductive function and/or cause feminisation by binding to oestrogen or androgen receptors; their binding to the thyroid ...
R H, Waring, R M, Harris
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