Cytotoxicity and Endocrine Disruption in Materials Used for Removable Orthodontic Retainers: A Comprehensive Review. [PDF]
Dent J (Basel)Chojnacka K, Mikulewicz M.
europepmc +1 more source
From Dark to Light - An Overview of Over 70 Years of Endocrine Disruption Research on Marine Mollusks. [PDF]
Front Endocrinol (Lausanne), 2022 Fodor I, Pirger Z.
europepmc +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Editorial: Endocrine disruption in marine species: unraveling pollution and climate change effects. [PDF]
Front Endocrinol (Lausanne)Bertucci JI, Blanco AM, Estêvão MD.
europepmc +1 more source
Behavioral Effects of Exposure to Phthalates in Female Rodents: Evidence for Endocrine Disruption? [PDF]
Int J Mol Sci, 2022 Adam N, Mhaouty-Kodja S.
europepmc +1 more source
Advanced Science, EarlyView.Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source
Toxic Alerts of Endocrine Disruption Revealed by Explainable Artificial Intelligence. [PDF]
Environ Health (Wash)Rosa LCS, Sarhan M, Pimentel AS.
europepmc +1 more source
Dichlorodiphenyltrichloroethane and the Adrenal Gland: From Toxicity to Endocrine Disruption. [PDF]
Toxics, 2021 Timokhina EP, Yaglov VV, Nazimova SV.
europepmc +1 more source
Delivery of Pleckstrin‐Homology Domains Suppresses PI3K/Akt Signaling and Breast Cancer Metastasis
Advanced Science, EarlyView.Current therapies curb tumor growth but not metastasis. Obscurin, a giant metastasis suppressor lost in breast cancer, restrains PI3K/Akt signaling but is impractical to restore. We deploy a mini‐obscurin, comprising the obscurin‐PH‐domain, which sequesters PI3K‐p85, potently suppressing invasion and metastasis.
Matthew Eason +12 more
wiley +1 more source