Results 21 to 30 of about 303,882 (203)

Rituximab in the treatment of Graves’ disease and endocrine ophthalmopathy. Opportunities and limitations

Научно-практическая ревматология, 2023
Rituximab is a chimeric (mouse and human) monoclonal antibody against B-lymphocytes (CD20). This drug is widely used in rheumatology in the treatment of rheumatoid arthritis, Sjogren’s syndrome, some systemic connective tissue diseases and vasculitis, as
T. S. Panevin, E. G. Zotkin, E. A. Troshina, G. V. Lukina   +3 more
doaj   +2 more sources

A Genomic Point Mutation in the Extracellular Domain of the Thyrotropin Receptor in Patients with Graves’ Ophthalmopathy [PDF]

, 1994
Orbital and pretibial fibroblasts are targets of autoimmune attack in Graves' ophthalmopathy (GO) and pretibial dermopathy (PTD). The fibroblast autoantigen involved in these peripheral manifestations of Graves' disease and the reason for the association
Sarkar, Gobinda, Bahn, Rebecca S., Heufelder, Armin E., Dutton, Charyl M., R. S. Bahn   +4 more
core   +1 more source

Eye blood flow deficiency is the key factor determining the form of the secondary glaucoma in endocrine ophthalmopath

Российский офтальмологический журнал, 2018
Endocrine ophthalmopathy patients constitute a group of risk for the development of secondary open angle glaucoma (SOAG). Disrupted blood circulation in the main vessels of the eye and the orbit is a mechanism triggering eye hypertension.
V. G. Likhvantseva, E. V. Korosteleva, I. V. Kovelenova, S. A. Budanova, A. . Ben Regeb   +4 more
doaj   +1 more source

Thyroid disorders and their role in the pathogenesis of glaucoma

Российский офтальмологический журнал, 2022
The literature analysis confirms the interrelationship of thyroid gland pathology and glaucoma. Patients with diffusetoxic goiter (DTG) and endemic goiter have an especially high risk of developing glaucoma, while those with autoimmune thyroiditis face a
T. V. Chernyakova, H. Y. Zargaryan, A. Yu. Brezhnev, O. N. Onufriychuk, I. R. Gazizova, А. V. Seleznev, А. V. Kuroyedov   +6 more
doaj   +1 more source

Transforming growth factor β1 (TGF-β1) in patients with endocrine ophthalmopathy and Graves’ disease: A predictor of treatment efficiency

Медицинская иммунология, 2022
Current therapeutic approaches to the treatment of endocrine ophthalmopathy (EOP) are based on nonspecific immunosuppression with glucocorticosteroids (GCs) and radiation therapy of the eye orbits.
N. Yu. Sviridenko, E. G. Bessmertnaya, I. M. Belovalova, M. S. Sheremeta, D. M. Babaeva, N. M. Malysheva, E. A. Troshina, G. A. Melnichenko   +7 more
doaj   +1 more source

Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]

, 1996
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Wenzel, Björn E., Heufelder, Armin E., Scriba, Peter C.   +2 more
core   +1 more source

Association between polymorphic markers in candidate genes and the risk of manifestationof endocrine ophthalmopathy in patients with Graves’ disease [PDF]

Терапевтический архив, 2018
Aim. To analyze the association between the polymorphic markers in CTLA4, TNF, IL10 and IL16 genes and the risk of manifestation of endocrine ophthalmopathy (EO) in patients with Graves’ disease (GD). Materials and methods.
N A Petunina, N S Martirosian, L V Trukhina, S V Saakyan, O G Panteleeva, A M Burdennyy, V V Nosikov   +6 more
doaj   +1 more source

Assessing the efficacy of various treatment regimens for patients with endocrine ophthalmopathy associated with Graves’ disease

Journal of Ophthalmology, 2022
Purpose: To assess the efficacy of various treatment regimens for patients with EO associated with Graves’ disease based on the retrospective analysis of clinical data, thyroid-stimulating hormone (TSH) receptor autoantibodies (TSHR-Ab) titers and ...
Yu. V. Buldygina , G. M. Terekhova, L. S. Strafun, I. I. Savosko, Z. G. Lysova, S. L. Shlyakhtych   +5 more
doaj   +1 more source

Optical coherence tomography and optical coherence tomography — angiography used in endocrine ophthalmopathy

Российский офтальмологический журнал, 2023
The literature review presents the results of optical coherence tomography and optical coherence tomography — angiography used for Graves’ orbitopathy. The data on the thickness of the inner layers of the retina, microcirculation in the peripapillary and
N. A. Gavrilova, N. Yu. Kutrovskaya, Kh. N. Salimova   +2 more
doaj   +1 more source

Diagnosis and treatment of Graves' disease

Медицинский совет, 2014
Graves' disease (Basedow's goiter, exophtalmic goiter) is a systemic autoimmune disease resulting from the production of stimulating antibodies to the thyroid stimulating hormone (TSH) receptor; it is clinically manifested in lesions of the thyroid gland
V. V. Fadeyev
doaj   +1 more source