Results 91 to 100 of about 611,039 (276)

Short‐term clinical responses in horses and ponies treated with canagliflozin: A clinical field study

Equine Veterinary Journal, EarlyView.
Abstract Background Treatment with the sodium‐glucose co‐transporter 2 (SGLT2) inhibitor canagliflozin in insulin dysregulated (ID) horses has shown promising results in randomised clinical trials. Larger field studies are needed to further evaluate treatment responses and potential adverse effects under real‐world conditions.
Moa Hällbom, Sanna Truelsen Lindåse, Monika Wartel, Johan Bröjer   +3 more
wiley   +1 more source

Pancreatic involvement in EPG5-related disorders

Molecular Genetics and Metabolism Reports
Vici syndrome is a severe neurodevelopmental multisystem disorder characterized by callosal agenesis, cataracts, cardiomyopathy, combined immunodeficiency and hypopigmentation. There may be additional variable involvement of other organs. VS is caused by
Dennis T. Famili, Gehad Elghazali, Emanuela Argili, Russell P. Saneto, Michael Harris, Oleg Gerasimenko, Julia Gerasimenko, Manolis Fanto, Hormos Salimi Dafsari, Heinz Jungbluth   +9 more
doaj   +1 more source

Balance between surgical and therapeutic treatment of chronic pancreatitis is a fundamental factor of functional outcome and quality of life of patients

Zaporožskij Medicinskij Žurnal, 2015
Relevance. The progressive course of CP with ductal hypertension causes severe pain, exo-, endocrine failure, reduces the quality of life and requires surgical treatment. Aim.
V. N. Klymenko , A. V. Klymenko, A. A. Steshenko   +2 more
doaj   +1 more source

Enzyme replacement therapy for pancreatic insufficiency: present and future

, 2011
Aaron Fieker1, Jessica Philpott1, Martine Armand21Division of Digestive Diseases, University of Oklahoma, OKC, OK, USA; 2INSERM, U476 "Nutrition Humaine et Lipides", Marseille, F-13385 France; Univ Méditerranée Aix-
Fieker A, Philpott J, Arm, M
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Laparoscopic pancreatic neck transection and double pancreatico-jejunostomy, an alternative surgical approach to chronic pancreatitis [PDF]

, 2019
Chronic pancreatitis is a benign inflammatory process that results symptoms pertaining to loss of endocrine and exocrine function. Pain poses a great challenge in the management of CP and intractable pain represents the main indication for surgical ...
강창무, 이우정
core   +1 more source

Pancreatic α‐cell dysfunction associated with equine insulin dysregulation

Equine Veterinary Journal, EarlyView.
Abstract Background Insulin dysregulation (ID) in horses is characterised by insulin resistance and exaggerated insulin responses, yet the underlying endocrine mechanisms remain incompletely understood. In humans, α‐cell dysfunction characterised by exaggerated glucagon secretion contributes to metabolic disease; however, the role of pancreatic α‐cell ...
Sanna Lindåse, Emma Strage, Josefin Söder, Johan Bröjer   +3 more
wiley   +1 more source

PANCREAS AS A SINGLE FUNCTIONALLY INTERRELATED ORGAN

Медицинский совет, 2017
Purpose of review: to demonstrate that in addition to the certain morphologic separation and functional independence of pancreatic islets and acinar tissue of the pancreas there is a strong interrelation between them.Major provisions:  the pancreas is an
S. A. Baranov, V. M. Nechaev
doaj   +1 more source

Screening and identification of novel peptides stimulating GLP‐1 secretion from plant proteins after simulated gastrointestinal digestion

Food Biomacromolecules, EarlyView.
Effects of digestive products of quinoa, oat, barley, and mungbean proteins on GLP‐1 secretion are investigated using STC‐1 cell and animal experiments, and novel GLP‐1 secretion‐stimulating peptides are successfully identified by column chromatography and LC–MS/MS.
Hongdong Song, Shaoxia Ren, Qiuyun Fu, Lei Xue, Kai Huang, Hongwei Cao, Zetang Zhang, Junhu Li, Xiao Guan   +8 more
wiley   +1 more source

Novel variation in the CEL gene causing impaired fasting glucose in a Chinese pediatric patient: case report and literature review

Frontiers in Endocrinology
ObjectiveCEL-related Maturity-Onset Diabetes of the Young (CEL-MODY) is a rare form caused by carboxyl ester lipase (CEL) gene mutations. It is characterized by dysglycemia and pancreatic exocrine dysfunction.
Chang Su, Yurong Piao, Congli Chen, Congli Chen, Di Wu, Rongmin Li, Yanmei Sang   +6 more
doaj   +1 more source

Treatment failure in celiac disease due to coexistent exocrine pancreatic insufficiency

, 1987
A 17-year-old white adolescent had a history of chronic diarrhea, delayed puberty, and growth failure. Investigations excluded cystic fibrosis, Shwachman syndrome, and endocrine causes of growth failure.
Weizman, Z., Cleghorn, G.J., Kopelman, H.R., Durie, P.R., Hamilton, J.R.   +4 more
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