Results 81 to 90 of about 611,039 (276)

Risk of pancreatic cancer in patients undergoing surgery for chronic pancreatitis

BMC Surgery, 2019
Background Chronic pancreatitis (CP) is considered to be a risk factor for pancreatic cancer. A retrospective study was conducted to evaluate the incidence of pancreatic cancer after surgery for CP and to determine the risk factors.
Zhenjiang Zheng, Yonghua Chen, Chunlu Tan, Nengwen Ke, Binqing Du, Xubao Liu   +5 more
doaj   +1 more source

Pancreatic insufficiency after different resections for benign tumours.

, 2008
BACKGROUND: Pancreatic resections for benign diseases may lead to long-term endocrine/exocrine impairment. The aim of this study was to compare postoperative and long-term results after different pancreatic resections for benign disease. METHODS: Between
CRIPPA, Stefano, MASCETTA, Giuseppe, R. Salvia, SALVIA, Roberto, FALCONI , MASSIMO, S. Crippa, P. Pederzoli, PEDERZOLI, Paolo, W. Mantovani, G. Mascetta, FALCONI, Massimo, MANTOVANI, William   +11 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Zinc status in chronic pancreatitis and its relationship with exocrine and endocrine insufficiency.

JOP : Journal of the pancreas, 2010
A major role of the pancreas in zinc homeostasis has been suggested.To assess erythrocyte zinc status in chronic pancreatitis and to correlate it with pancreatic exocrine and endocrine insufficiency.One hundred and one patients with chronic pancreatitis (34 alcoholic chronic pancreatitis, 67 tropical chronic pancreatitis) were prospectively studied ...
Banavara Narasimhamurthy, Girish, Gopalakrishna, Rajesh, Kannan, Vaidyanathan, Vallath, Balakrishnan   +3 more
openaire   +2 more sources

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Age-Related Alterations of Immunoreactive Pancreatic Cationic Trypsinogen in Sera From Cystic-Fibrosis Patients with and Without Pancreatic Insufficiency

, 1986
Serum immunoreactive cationic trypsinogen levels were determined in 99 control subjects and 381 cystic fibrosis (CF) patients. To evaluate the status of the exocrine pancreas all CF patients had previously undergone fecal fat balance studies and/or ...
M L Corey, Forstner, G.G., Corey, M.L., D J Moore, Moore, D.J., G G Forstner, Corey, ML, K J Gaskin, P R Durie, Wong, SS, Moore, DJ, Cleghorn, GJ, G J Cleghorn, Cleghorn, G.J., Gaskin, KJ, Wong, S.S., Gaskin, K.J., Forstner, GG, Durie, P.R., S S Wong, Durie, PR   +20 more
core   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Russian consensus on exo- and endocrine pancreatic insufficiency after surgical treatment

, 2020
© 2018 Media Sphera Publishing Group. All rights reserved. The Russian consensus on exo- and endocrine pancreatic insufficiency after surgical treatment was prepared on the initiative of the Russian "Pancreatic Club" on the Delphi method. His goal was to

core  

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

Clinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source