Environmental chemical exposures and breast cancer [PDF]
As a hormone-sensitive condition with no single identifiable cause, breast cancer is a major health problem. It is characterized by a wide range of contributing factors and exposures occurring in different combinations and strengths across a lifetime ...
Plant, J, Stanley, E, Voulvoulis, N
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Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and regeneration [PDF]
Type 2 diabetes (T2D) is a disease characterized by impaired insulin secretion. The Wnt signaling transcription factor Tcf7l2 is to date the T2D-associated gene with the largest effect on disease susceptibility.
Argenton, Francesco +11 more
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Silent Spring - the lost call [PDF]
The "silence" in Rachel Carson's Silent Spring1 alludes to the demise of bird populations through reproductive problems and death resulting from exposure to the pesticides of that time, many of which are endocrine active.
Mary Ann Ottinger, Michael J. Quinn
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Cellular distribution and amount of chromogranin A in bovine endocrine pancreas [PDF]
We determined the cellular distribution and the amount of chromogranin A in endocrine cells of bovine pancreas using a polyclonal antibody against bovine adrenomedullary chromogranin A. The relative amounts of chromogranin A in the different cells of the
Ehrhart, M. +3 more
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The impact of process variables on the removal of PBDEs and NPEOs during simulated activated sludge treatment [PDF]
Sewage effluent is known to be a major source of endocrine disrupting compounds entering the aquatic environment. More efficient wastewater treatment could reduce the environmental load but, in order to achieve this factors determining compound behaviour
Langford, KH, Lester, JN, Scrimshaw, MD
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Update on male reproductive endocrinology. [PDF]
Practitioners of male reproductive and sexual medicine must have an intimate understanding of the physiology of male reproductive endocrinology, as such a knowledge is the cornerstone on which hormonal treatments are based.
Clavijo, Raul, Hsiao, Wayland
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Endocrinology and physiology of pseudocyesis [PDF]
This literature review on pseudocyesis or false pregnancy aims to find epidemiological, psychiatric/psychologic, gynecological and endocrine traits associated with this condition in order to propose neuroendocrine/endocrine mechanisms leading to the ...
Cano, Antonio +3 more
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Immunity is believed to share limited resources with other physiological functions and this may partly account for the fitness costs of reproduction. Previous studies have shown that the acquired immunity of female common eiders (Somateria mollissima) is
Ahima +45 more
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Evidence for a GABAergic system in rodent and human testis: Local GABA production and GABA receptors [PDF]
The major neurotransmitter of the central nervous system, gamma-aminobutyric acid (GABA), exerts its actions through GABA(A), GABA(B) and GABA(C) receptors.
Calandra, Ricardo S. +7 more
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Timing of maternal exposure and fetal sex determine the effects of low-level chemical mixture exposure on the fetal neuroendocrine system in sheep [PDF]
We have shown that continuous maternal exposure to the complex mixture of environmental chemicals (ECs) found in human biosolids (sewage sludge), disrupts mRNA expression of genes crucial for development and long-term regulation of hypothalamo-pituitary ...
Bellingham, M. +7 more
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