Results 81 to 90 of about 2,258,907 (387)

Nerve growth factor: basic findings and clinical trials [PDF]

, 1999
The nerve growth factor is the first-discovered and best-characterized member of the family of neurotrophins. In the introduction of this article we present a brief biographic view of past and present studies of Rita Levi-Montalcini on nerve growth ...
Aloe, Luigi, Micera, Alessandra
core   +2 more sources

Endocrine FGFs: evolution, physiology, pathophysiology, and pharmacotherapy

Frontiers in Endocrinology, 2015
The human fibroblast growth factor (FGF) family comprises 22 structurally related polypeptides that play crucial roles in neuronal functions, development, and metabolism.
Nobuyuki eItoh, Hiroya eOhta, Morichika eKonishi   +2 more
doaj   +1 more source

Endocrine system on chip for a diabetes treatment model

Biofabrication, 2017
The endocrine system is a collection of glands producing hormones which, among others, regulates metabolism, growth and development. One important group of endocrine diseases is diabetes, which is caused by a deficiency or diminished effectiveness of ...
Dao Thi Thuy Nguyen, D. van Noort, In-Kyung Jeong, Sungsu Park   +3 more
semanticscholar   +1 more source

Immunoregulatory mechanisms of the arachidonic acid pathway in cancer

FEBS Letters, EarlyView.
The central role of the arachidonic acid (AA) pathway in anticancer immunity. Enzymes and metabolites of the AA pathway can play both immunosuppressive and immunostimulatory roles in the tumor microenvironment. Therefore, their tailored targeting could be beneficial as a standalone therapy or in combination with current cancer immunotherapy.
Maria Tredicine, Matteo Mucci, Antonio Recchiuti, Domenico Mattoscio   +3 more
wiley   +1 more source

Pediatric Endocrine Hypertension Related to the Adrenal Glands

The Ewha Medical Journal, 2023
Endocrine causes of pediatric hypertension are relatively rare but important because of their distinct treatment options. Adrenal diseases accompanied by an excess of mineralocorticoids, glucocorticoids, and ...
Hwa Young Kim, Jaehyun Kim
doaj   +1 more source

Extra virgin olive oil and cardiovascular diseases: benefits for human health [PDF]

, 2017
The cardioprotective properties of Mediterranean Diet were demonstrated for the first time from the Seven Country Study. In the last few decades, numerous epidemiological studies, as well as intervention trial, confirmed this observation, pointing out ...
Cammisotto, Vittoria, Carnevale, Roberto, Castellani, Valentina, D'Amico, Alessandra, Fianchini, Luca, Nocella, Cristina, Novo, Marta, Stefanini, Lucia, Violi, Francesco   +8 more
core   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

Physical activity and hypocaloric diet recovers osteoblasts homeostasis in women affected by abdominal obesity. [PDF]

, 2016
Obesity is a multifactorial disease linked to metabolic chronic disorders such as diabetes, and hypertension. Also, it has recently been associated with skeletal alterations and low bone mineral density.
Baldari, C, Bimonte, VIVIANA MARIA, Di Luigi, L, Donini, Lorenzo Maria, Emerenziani, GIAN PIETRO, Fittipaldi, Simona, Fornari, Rachele, Greco, Ea, Guidetti, L, Lenzi, Andrea, Marocco, Chiara, Migliaccio, S., Nicolai, E, Poggiogalle, Eleonora   +13 more
core   +1 more source

The adverse role of endocrine disrupting chemicals in the reproductive system

Frontiers in Endocrinology
Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation and changes in lifestyle, the occurrence of these diseases is closely connected to exposure to harmful ...
Jing Pan, Pengfei Liu, Xiao Yu, Zhongming Zhang, Jinxing Liu   +4 more
semanticscholar   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source