Results 31 to 40 of about 119,873 (307)

Paediatric endocrinology - prospectives and near future [PDF]

, 2014
It is my greatest pleasure to introduce the papers devoted to Paediatric Endocrinology, coming in the current issue of Scripta Scientifica Medica!Paediatric Endocrinology is a relatively new but quickly and steadily developing paediatric subspecialty ...
Iotova, Violeta; Medical University of Varna
core   +1 more source

Molecular Research on Genes Involved in Metabolic Diseases

, 2023
Numerous genes involved in different metabolic diseases have been identified, and this number is increasing [...
Francisco Lara-Hernandez, Javier Chaves, Luis Alvarez, Ana-Barbara Garcia-Garcia   +3 more
core   +1 more source

Fibrosis-4 Index Is Closely Associated with Arterial Damage and Future Risk of Coronary Heart Disease in Type 2 Diabetes

International Journal of Hypertension, 2022
This study evaluated the association between fibrosis-4 (FIB 4) index and arterial damage or future risk of coronary heart disease (CHD) in type 2 diabetes. The study subjects were 253 patients with type 2 diabetes. The FIB4 index, as a marker of hepatic
Kentaro Watanabe, Noe Takakubo, Taro Saigusa, Akiko Nagasawa, Midori Yamana, Midori Ojima, Wataru Kameda, Shinji Susa, Kenichi Ishizawa, Hisamitsu Ishihara   +9 more
doaj   +1 more source

Relationship between NAFLD and coronary artery disease: A Mendelian randomization study

Hepatology, EarlyView., 2022
Abstract Background and Aims There is an ongoing debate on whether NAFLD is an active contributor or an innocent bystander in the pathogenesis of coronary artery disease (CAD). The aim of the present study was to assess the causal relationship between NAFLD and CAD.
Zhewen Ren, Pomme I. H. G. Simons, Anke Wesselius, Coen D. A. Stehouwer, Martijn C. G. J. Brouwers   +4 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride‐rich lipoprotein metabolism

Hepatology, EarlyView., 2022
Hepatic APOF transcript levels correlate inversely with plasma TG and hepatic steatosis in humans. ApoF expression in mice promotes VLDL‐TG production and lipoprotein remnant clearance in mice. Abstract Background NAFLD affects nearly 25% of the global population. Cardiovascular disease (CVD) is the most common cause of death among patients with NAFLD,
Audrey Deprince, Nathalie Hennuyer, Sander Kooijman, Amanda C. M. Pronk, Eric Baugé, Viktor Lienard, An Verrijken, Eveline Dirinck, Luisa Vonghia, Eloïse Woitrain, Niels J. Kloosterhuis, Eléonore Marez, Pauline Jacquemain, Justina C. Wolters, Fanny Lalloyer, Delphine Eberlé, Sandrine Quemener, Emmanuelle Vallez, Anne Tailleux, Mostafa Kouach, Jean‐Francois Goossens, Violeta Raverdy, Bruno Derudas, Jan Albert Kuivenhoven, Mikaël Croyal, Bart van de Sluis, Sven Francque, François Pattou, Patrick C. N. Rensen, Bart Staels, Joel T. Haas   +30 more
wiley   +1 more source

CircLDLR acts as a sponge for miR-667-5p to regulate SIRT1 expression in non-alcoholic fatty liver disease

Lipids in Health and Disease, 2022
Background Non-alcoholic fatty liver (NAFLD) is a complex metabolic disease characterized by fatty degeneration of hepatocytes. Circular RNAs (circRNAs) have been reported to be essential for (NAFLD progression.
Xinlu Yuan, Yanyan Li, Song Wen, Chenglin Xu, Congcong Wang, Yanju He, Ligang Zhou   +6 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Noninvasive tests for nonalcoholic fatty liver disease in a multi‐ethnic population: The HELIUS study

Hepatology Communications, EarlyView., 2022
Abstract Nonalcoholic fatty liver disease (NAFLD) is increasing in prevalence and severity globally, prompting noninvasive testing, yet limited data exist on noninvasive liver tests (NITs) including transient elastography (TE) in ethnically diverse populations.
Anne‐Marieke van Dijk, Yasaman Vali, Anne Linde Mak, Henrike Galenkamp, Max Nieuwdorp, Bert‐Jan van den Born, Adriaan Georgius Holleboom   +6 more
wiley   +1 more source

Clinical Characteristics and Development of Complications Differ Between Adult-Onset and Child–Adolescent-Onset Type 1 Diabetes: A Report From a Tertiary Medical Center in Türkiye

Journal of Diabetes Research
Conclusion: Clinical presentation and prognosis differ in adult-onset and child–adolescent-onset T1DM. Low initial C-peptide may predict the development of microvascular and macrovascular complications.
Ramazan Çakmak, Özge Telci Çaklılı, Ayşe Merve Ok, Ümmü Mutlu, Göktuğ Sarıbeyliler, Vefa Seferova Nasifova, Ersel Bilgin, Aylin Çoşkun, Damla Yenersu Guzey, Utku Erdem Soyaltin, Servet Yüce, Hülya Hacışahinoğulları, Gülşah Yenidünya Yalın, Özlem Soyluk Selçukbiricik, Nurdan Gül, Ayşe Kubat Üzüm, Kubilay Karşıdağ, Nevin Dinççağ, Mehmet Temel Yılmaz, Ilhan Satman   +19 more
doaj   +1 more source