Results 51 to 60 of about 119,873 (307)

Assessment of sublingual microcirculation for the screening of diabetic nephropathy

Diabetology & Metabolic Syndrome, 2022
Objective To investigate the potential of employing sublingual microcirculation as an early noninvasive screening technique for diabetic nephropathy (DN).
Qiang Li, XiaoXiao Liu, Mengxiao Jia, Fang Sun, Yingsha Li, Hexuan Zhang, Xiaoli Liu, Hongbo He, Zhigang Zhao, Zhencheng Yan, Zhiming Zhu   +10 more
doaj   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Impact of Lipoprotein(a) on Macrovascular Complications of Diabetes in a Multiethnic Population in the French Amazon

Journal of Diabetes Research, 2023
Background and Aims. In French Guiana, the prevalence of diabetes is around 10%, and cardio and neurovascular pathologies are the first medical cause of early mortality.
Sabrina Dordonne, Mayka Mergeayfabre, Nezha Hafsi, Andre Ntoutoum, Clara Salazar-Cardozo, Olivier Casse, Marianne Hounnou, Antoine Adenis, Jean-Markens Aurelus, Caroline Misslin-Tristch, Jean-François Carod, Bertrand De Toffol, Jean François Lienne, Magalie Demar, Mathieu Nacher, Nadia Sabbah   +15 more
doaj   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Acute response to endurance exercise stress: Focus on catabolic/anabolic interplay between cortisol, testosterone, and sex hormone binding globulin in professional athletes [PDF]

Journal of Medical Biochemistry, 2019
Background: Endocrine system plays a major role in both permissive and regulatory activities in order to adequately respond to physical stress of exercise.
Popović Bojana, Popović Dejana, Macut Đuro, Božić-Antić Ivana, Isailović Tatjana, Ognjanović Sanja, Bogavac Tamara, Elezović-Kovačević Valentina, Ilić Dušan, Petrović Mirjana, Damjanović Svetozar   +10 more
doaj  

Recommendations of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism for the diagnosis of Cushing’s disease in Brazil [PDF]

Archives of Endocrinology and Metabolism, 2016
Although it is a rare condition, the accurate diagnosis and treatment of Cushing's disease is important due to its higher morbidity and mortality compared to the general population, which is attributed to cardiovascular diseases, diabetes mellitus and infections.
Machado, Márcio Carlos, Fragoso, Maria Candida Barisson Vilares, Moreira, Ayrton Custódio, Boguszewski, César Luiz, Vieira Neto, Leonardo, Naves, Luciana Ansaneli, Vilar, Lucio, Araújo, Luiz Antônio de, Czepielewski, Mauro Antonio, Gadelha, Monica R., Musolino, Nina Rosa Castro, Miranda, Paulo Augusto Carvalho, Bronstein, Marcello Delano, Oliveira Júnior, Antônio Ribeiro   +13 more
openaire   +6 more sources

Predicting health-related quality of life of parents of children with inherited metabolic diseases

, 2009
The aim of this study was to examine medical, socio-demographic and psychosocial determinants of health-related quality of life (HRQoL) of parents of children with metabolic diseases.
Bosch, Annet M., Hatzmann, Janneke, Heymans, Hugo S. A., Grootenhuis, Martha A., Valstar, Marlies J., Wijburg, Frits A.   +5 more
core   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

Advanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu, Yingyu Zhang, Xianwei Zhang, Mengxin Zhang, Fei Zhang, Jushan Sun, Yahui Yang, Kangbo Liu, Peng Wang, Shuying Luo, Wancun Zhang   +10 more
wiley   +1 more source

Subclinical Hypothyroidism is not Associated with Hyperhomocysteinyemia

Endocrinology Research and Practice, 2008
Objective: There are controversial reports regarding subclinical hypothyroidism and its association with hyperhomocysteinyemia. We aimed to evaluate whether subclinical hypothyroidism is associated with hyperhomocysteinyemia and sought to explain the ...
Mustafa Şahin, Aslı Doğruk, Mustafa Kulaksızoğlu, Alptekin Gürsoy, Derun Ertuğrul, Emre Bozkırlı, Hamiyet Yılmaz, Neslihan B. Tütüncü, Nilgün D. Güvener   +8 more
doaj   +2 more sources

Gestational diabetes as an inter-generational cardiometabolic risk factor: spotlight on emerging exerkines

Cardiovascular Diabetology
Gestational diabetes mellitus (GDM) is an increasingly prevalent global health condition, driven by rising maternal age and the obesogenic environment, currently affecting approximately 14% of pregnancies worldwide.
Pamela Senesi, Livio Luzi, Andrea Sonaglioni, Flavia Alberti, Elisa Cipponeri, Anna Ferrulli   +5 more
doaj   +1 more source