Results 71 to 80 of about 119,873 (307)
Background: Endocrine and metabolic diseases especially diabetes have become focus areas for public health professionals. Indian Journal of Endocrinology and Metabolism (IJEM), a publication of Endocrine Society of India, is a peer-reviewed online ...
Kanica Kaushal, Sanjay Kalra
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NDFIP2 recruits NEDD4 to promote K48‐linked ubiquitination and proteasomal degradation of DDX3X, leading to R‐loop accumulation and CTCF‐dependent suppression of GNG13 transcription. Consequently, PI3K/AKT signaling, EMT, stemness, and colorectal cancer metastasis are inhibited.
Enjian Zhang +12 more
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Skeletal muscle, traditionally recognized for its motor function, has emerged as a key endocrine organ involved in metabolic regulation and interorgan communication. This narrative review addresses the dual role of muscle as a target tissue for classical
Iglesias, Pedro, Pedro Iglesias
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Metabolic Disorders in Menopause
Menopause is an aging process and an important time equivalent to one-third of a woman’s lifetime. Menopause significantly increases the risk of cardiometabolic diseases, such as obesity, type 2 diabetes, cardiovascular diseases, non-alcoholic ...
Hyuntae Park +3 more
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ABSTRACT ADNP‐related Helsmoortel–Van der Aa syndrome (ADNP‐related HVDAS) is a single gene form of autism spectrum disorder (ASD) caused by pathogenic sequence variants in the activity‐dependent neuroprotective protein (ADNP) gene. In addition to ASD, ADNP‐related HVDAS is associated with a wide range of cognitive, behavioral, and physical health ...
Jarrett Fastman +11 more
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Background Mutations in the aggrecan (ACAN) gene can cause short stature (with heterogeneous clinical phenotypes), impaired bone maturation, and large variations in response to growth hormone (GH) treatment. For such cases, long-term longitudinal therapy
Dandan Xu +10 more
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Jørn Ditzel, Hans-Henrik LervangDepartment of Endocrinology, Center for Prevention of Struma and Metabolic Diseases, Aalborg University Hospital, Aarhus University, Aalborg, DenmarkAbstract: Recent studies on diabetes and metabolic syndrome ...
Hans-Henrik Lervang +2 more
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Genetic and Population Analyses Implicate Thyroid‐Related Regulation of RNF144B in Chondrocalcinosis
Objective Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5% to 15% of the general population and has recently been identified as an osteoarthritis risk factor. However, its biologic pathways remain unclear.
Yahong Wu +15 more
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Previously we have reported decrease in hepatic and pancreatic fat fraction with Dapagliflozin (DAPA). In this research, we evaluated the effects of Metformin intervention for 120 days on hepatic fat fraction (HFF) and pancreatic fat fraction (PFF ...
Koel Dutta +7 more
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Endocrinology, Diabetes, and Metabolic Disorders
Background: Endocrinology, diabetes, and metabolic disorders represent a rapidly expanding area of clinical medicine due to the increasing global burden of obesity, type 2 diabetes mellitus, thyroid disorders, adrenal diseases, pituitary dysfunction ...
Dr. Partha Pratim Adak
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