Results 91 to 100 of about 119,873 (307)

Lifespan Pancreas Morphology for Control Versus Type 2 Diabetes Using AI on Largescale Clinical Imaging

Clinical Anatomy, EarlyView.
ABSTRACT Understanding how pancreas size and shape change with normal aging is critical for establishing a baseline to detect deviations in type 2 diabetes and other pancreatic disease. We measure pancreas size and shape using morphological measurements from early development through aging (ages 0–90).
Lucas W. Remedios, Chloe Cho, Trent M. Schwartz, Dingjie Su, Gaurav Rudravaram, Chenyu Gao, Aravind R. Krishnan, Adam M. Saunders, Michael E. Kim, Shunxing Bao, Thomas A. Lasko, Alvin C. Powers, Bennett A. Landman, John Virostko   +13 more
wiley   +1 more source

Refractory Hypothyroidism: Unexpected Outcome During Treatment of Giant Cell Arteritis

Clinical Case Reports
Refractory hypothyroidism is not uncommon in patients treated with oral levothyroxine, and it represents a challenge for clinicians as regards a physiopathological diagnosis and the most appropriate long‐term therapeutic management in order to restore ...
Elise Deprince, Solange Grunenwald, Celine Mouly, Julie Benoit, Philippe J. Caron   +4 more
doaj   +1 more source

Paradigm Shift in the Management of Metabolic Diseases—Next-Generation Incretin Therapy

, 2023
Recently impressive weight loss has been reported for novel incretin therapies based on dual-and triple-hormone receptor coagonists. These agents have potential as being positioned as early therapeutics for metabolic diseases for which weight loss is ...
Ahrén, Bo, Lund University., Ahrén, Bo,   +2 more
core   +1 more source

Normative Measures of Colon Length in Children With Inflammatory Bowel Disease, Aged 11–17 Years, Based on MRI

Clinical Anatomy, EarlyView.
ABSTRACT To better understand (abnormal) colonic anatomy on imaging, data on normal colonic anatomy in the unaffected population are crucial. We assessed colon lengths in children without constipation on MRI. This retrospective study included patients (< 18 years), who underwent MRI‐enterography between 2016 and 2020 for suspected inflammatory bowel ...
Charlotte A. L. Jonker, R. R. Gorter, M. A. Benninga, I. J. N. Koppen, C. S. de Jonge, J. R. de Jong, J. van Schuppen   +6 more
wiley   +1 more source

Association of GH and IGF-1 Levels with Increased Carotid Intima-Media Thickness and Cardiovascular Risk Scores in Acromegaly: A Cross-Sectional Study

International Journal of General Medicine
Emine Kartal Baykan,1 P&inodot;nar Akhanl&inodot;,1 Serpil Usta Çiftel,1 Ali Pir,1 Ömer Faruk Tulun,1 &Idot;lker Yavuz,1 Elif Akyüz Kotan,1 Mehmet Zeki Çalg&inodot;n,1 Ahmed Ramiz Baykan2 1Department of Endocrinology and Metabolic ...
Kartal Baykan E, Akhanlı P, Usta Çiftel S, Pir A, Tulun ÖF, Yavuz İ, Akyüz Kotan E, Çalgın MZ, Baykan AR   +8 more
doaj  

Navigating adulthood with PKU: metabolic outcomes, quality of life, and mental health 4.5 years post-transition

Orphanet Journal of Rare Diseases
Introduction Adult care for individuals with phenylketonuria (PKU) remains limited, as many centers prioritize pediatric patients. Structured transition into adult care is essential to maintain metabolic stability, adherence, and monitor comorbidities ...
Antonia Albers, Nadine Kuniß, Christof Kloos, Gunter Wolf, Sebastian Schmidt, Nicolle Müller   +5 more
doaj   +1 more source

Systemic Diseases and the Eye: A Translational Perspective on Diabetes

Chronic Diseases and Translational Medicine, EarlyView.
The eye–brain–cardiometabolic axis in diabetes: retinal biomarkers as indicators of systemic disease. ABSTRACT Diabetes mellitus is a global chronic disease that affects the whole body and not just glucose metabolism. In diabetes, non‐invasive ocular changes can help understand microvascular, neurodegenerative, and inflammatory processes. This analysis
Matteo Capobianco, Marco Zeppieri, Simonetta Gaia Nicolosi, Niccolò Castellino, Francesco Cappellani, Irene Gattazzo, Caterina Gagliano   +6 more
wiley   +1 more source

Increased Insulin Action, Glucose Metabolism and Muscle Function in Supervillin‐Knockout and Supervillin‐Mutant Mice

Cytoskeleton, EarlyView.
ABSTRACT We here describe mouse models with complementary homozygous Svil mutations. In skeletal muscle, Svil‐Mut mice express the Svil‐encoded N‐terminus fused to the βgal‐neo gene‐trap tag and lack the highly conserved archvillin C‐terminus; Svil‐KO mice lack expression of all known Svil‐encoded proteins; and Svil‐LoxP mice contain loxP sites for ...
Tara C. Smith, Lauren A. Tauer, Randall H. Friedline, Xiaodi Hu, Duy Tran, Yangyi E. Luo, Nacima Hadjout‐Rabi, Elisabeth R. Barton, Jason K. Kim, Elizabeth J. Luna   +9 more
wiley   +1 more source

High Prevalence of Thyroid Dysfunction and Autoimmune Thyroiditis in Adolescents After Elimination of Iodine Deficiency in Eastern Black Sea Region of Turkey

Endocrinology Research and Practice, 2006
In the present study we evaluated the effects of iodine intake on the prevalence of thyroid dysfunction, autoimmunity and goiter in two regions with different iodine status after two years of iodinisation in Turkey.
Rıfat Emral, Mehmet Baştemir, Gürbüz Erdoğan, Sevim Güllü   +3 more
doaj   +2 more sources

Endocrinology in maternal-fetal synchronization and developmental origins of susceptibility to metabolic diseases

Endocrine Journal
The biological clock enables organisms to align their intrinsic rhythms with daily environmental cycles thereby maintaining homeostasis and imparting resilience against metabolic derangements. Endocrine hormones and neural networks are key mediators of temporal coordination across remote tissues.
Kinouchi, Kenichiro, Itoh, Hiroshi
openaire   +3 more sources