Results 1 to 10 of about 3,012,914 (272)
An endocytic-secretory cycle participates in Toxoplasma gondii in motility. [PDF]
PLoS Biology, 2019 Apicomplexan parasites invade host cells in an active process involving their ability to move by gliding motility. While the acto-myosin system of the parasite plays a crucial role in the formation and release of attachment sites during this process ...
Simon Gras +6 more
doaj +7 more sources
PLoS Pathogens, 2015 Influenza virus particles are assembled at the plasma membrane in concert with incorporation of the virus genome, but the details of its spatio-temporal regulation are not understood.
Atsushi Kawaguchi +4 more
doaj +6 more sources
Constitutive Endocytic Cycle of the CB1 Cannabinoid Receptor [PDF]
Journal of Biological Chemistry, 2004 The CB1 cannabinoid receptor (CB1R) displays a significant level of ligand-independent (i.e. constitutive) activity, either when heterologously expressed in nonneuronal cells or in neurons where CB1Rs are endogenous.
Christophe Leterrier +4 more
semanticscholar +5 more sources
Apicomplexan motility depends on the operation of an endocytic-secretory cycle [PDF]
bioRxiv, 2018 Apicomplexan parasites invade host cells in an active process, involving their ability to move by gliding motility and invasion. While the acto-myosin-system of the parasite plays a crucial role in the formation and release of attachment sites during ...
Simon Gras +4 more
semanticscholar +4 more sources
Spatial restriction of receptor tyrosine kinase activity through a polarized endocytic cycle controls border cell migration [PDF]
Proceedings of the National Academy of Sciences, 2010 Border cell migration is a stereotyped migration occurring during the development of the Drosophila egg chamber. During this process, a cluster composed of six to eight follicle cells migrates between nurse cells toward the oocyte.
Gloria Assaker +4 more
semanticscholar +5 more sources
Possible roles of the endocytic cycle in cell motility [PDF]
Journal of Cell Science, 2007 Starving, highly motile Dictyostelium cells maintain an active endocytic cycle, taking up their surface about every 11 minutes. Cell motility depends on a functional NSF (N-ethylmaleimide sensitive factor) protein - also essential for endocytosis and membrane trafficking generally - and we, therefore, investigated possible ways in which the endocytic ...
David Traynor, Robert R. Kay
semanticscholar +4 more sources
Unconventional Functions for Clathrin, ESCRTs, and Other Endocytic Regulators in the Cytoskeleton, Cell Cycle, Nucleus, and Beyond: Links to Human Disease [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 The roles of clathrin, its regulators, and the ESCRT (endosomal sorting complex required for transport) proteins are well defined in endocytosis. These proteins can also participate in intracellular pathways that are independent of endocytosis and even independent of the membrane trafficking function of these proteins.
Frances M. Brodsky +3 more
semanticscholar +4 more sources
Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity [PDF]
Leukemia, 2003 Multicenter phase II trials with Gemtuzumab Ozogamicin (GO/Mylotarg), consisting of a CD33 antibody linked to the cytotoxic drug calicheamicin, have shown a 30% overall response rate in relapsed acute myeloid leukemia patients. However, no clear correlation was observed between CD33 expression on leukemic blasts and response to GO therapy.
Inge Jedema +6 more
semanticscholar +5 more sources
Molecular Biology of the Cell, 1996 Regulation of inositol uptake activity in Saccharomyces cerevisiae during the growth cycle was examined. Activity increased as the cell population transited from lag phase to exponential growth, and continued to increase until late exponential phase. The increase in activity was due to increased transcription of the ITR1 gene and synthesis of the Itr1
Katherine Robinson +3 more
semanticscholar +5 more sources
pH‐Independent Endocytic Cycling of the Chemokine Receptor CCR5 [PDF]
Traffic, 2004 Following agonist activation, the chemokine receptor CCR5 is internalised through clathrin‐coated pits and delivered to recycling endosomes. Subsequently, ligand‐ free and resensitised receptors are recycled to the cell surface. Currently little is known of the mechanisms regulating resensitisation and recycling of this G‐protein coupled receptor. Here
Nathalie Signoret +3 more
openalex +4 more sources