Results 201 to 210 of about 64,404 (299)

Ultrastructural Insights Into a Candidatus Parilichlamydia sp. Infection of Gill Goblet Cells in Greater Amberjack

Journal of Fish Diseases, EarlyView.
ABSTRACT Despite recent genomic studies and increased molecular data, epitheliocystis remains an enigmatic fish disease with no experimental in vitro or in vivo models to aid the advancement of research. In this study, we revert to a classical microscopical approach and screen with the electron microscope the epitheliocystis lesions caused by a Ca ...
Maria Chiara Cascarano, Papadogiorgaki Sevasti, Pantelis Katharios   +2 more
wiley   +1 more source

Alzheimer's genetic risk factor Bin1 controls synapse vesicle exo-endocytosis in inhibitory synapses.

Cell Rep
Barata MA, Perdigão C, Ramalho J, Gomes ER, Guimas Almeida C.   +4 more
europepmc   +1 more source

Interconnections of insulin/IGF-1 signaling and autophagy abnormalities in Alzheimer's disease. [PDF]

Alzheimers Dement
Liao W, Xuan J, Ryu WI, Bormann MK, Lee Y, Dion H, Evangelista E, Li R, Trambaiolli L, Liu J, Siegel AJ, Forester BP, Cohen BM, Sonntag KC.   +13 more
europepmc   +1 more source

From cells to pixels: A decision tree for designing bioimage analysis pipelines

Journal of Microscopy, EarlyView.
Abstract Bioimaging has transformed our understanding of biological processes, yet extracting meaningful information from complex datasets remains a challenge, particularly for biologists without computational expertise. This paper proposes a simple general approach, to help identify which image analysis methods could be relevant for a given image ...
Elnaz Fazeli, Robert Haase, Michael Doube, Kota Miura, David Legland   +4 more
wiley   +1 more source

Integrin beta 1 facilitates non-enveloped hepatitis E virus cell entry through the recycling endosome. [PDF]

Nat Commun
Fu R, Jordan P, Engels Z, Weihs JA, Mürle J, Chi H, Burbano de Lara S, Helm B, Klöhn M, Hu J, Freistaedter A, Boettler T, Binder M, Klingmüller U, Steinmann E, Lozach PY, Tubiana T, Lemon SM, Dao Thi VL.   +18 more
europepmc   +1 more source

Gene Expression Divergence Between Locally Adapted Inland Annual and Coastal Perennial Ecotypes of Mimulus guttatus Across Developmental Stages

Molecular Ecology, EarlyView.
ABSTRACT The action of natural selection across heterogeneous natural landscapes drives local adaptation and the formation of plant ecotypes, the precursors to new species. Plant ecotypes typically differ significantly in morphology, physiology, and development, yet our understanding of their underlying genetic basis remains limited.
Jason D. Olsen, Billie A. Gould, Yani Chen, David B. Lowry   +3 more
wiley   +1 more source

Characterizing the Membrane Assembly of ASGPR Related to Mediated Endocytosis Using TriGalNAc-Probe-Based Super-Resolution Imaging. [PDF]

JACS Au
Chen J, Wang J, Sui B, Jiang P, Wang X, Wang H, Liang F.   +6 more
europepmc   +1 more source

Identification of potential cell surface targets in patient‐derived cultures toward photoimmunotherapy of high‐grade serous ovarian cancer

Photochemistry and Photobiology, EarlyView.
Through mRNA sequencing, proteomics, and flow cytometry, we identified potential cell surface targets toward tumor‐targeted, activatable photoimmunotherapy (taPIT) in advanced high‐grade serous ovarian cancers (HGSOCs) with low EGFR expression. The reliance on EGFR overexpression has been a major limitation of taPIT, which this study seeks to address ...
Sudip Timilsina, Anish Raju Amara, Rafay Abu, Bryan Q. Spring   +3 more
wiley   +1 more source

Adducin-1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity. [PDF]

Adv Sci (Weinh)
Jiang M, Zou J, Jin Y, Jiang C, Tu S, Chen T, Guo J, Cheng Y, Jin M, Chen H, Zhou H.   +10 more
europepmc   +1 more source

Presynaptic quantal size enhancement counteracts post‐tetanic release depression

The Journal of Physiology, EarlyView.
Abstract figure legend Sustained high‐frequency stimulation decreases the number of synaptic vesicles that fuse per action potential at the Drosophila neuromuscular junction. However, the postsynaptic response remains largely unchanged. An increased postsynaptic response to individual vesicles, likely driven by an increase in vesicle size resulting ...
Anu G. Nair, Nasrin Bollmohr, Levin Schökle, Jennifer Keim, José María Mateos Melero, Martin Müller   +5 more
wiley   +1 more source