Results 201 to 210 of about 3,012,914 (272)

Multivesicular body subunit 12B (MVB12B) overexpression represses proliferation and migration in bladder urothelial carcinoma. [PDF]

Transl Cancer Res
Li X, Cen C, Li R, Su Q, Mo W, Lin F.
europepmc   +1 more source

The Calcium‐Binding Protein S100A10 (p11) Is Required for Normal Motor Performance by Regulating Vesicle Dynamics at Excitatory Synapses

Acta Physiologica, Volume 242, Issue 2, February 2026.
ABSTRACT Aim Identifying interactors in sensorimotor processing and neurotransmission remains a current challenge for understanding neural information processing and brain function. Methods To evaluate the role of p11 in sensorimotor processing and excitatory synaptic neurotransmission, neuron‐specific lentivirus‐directed p11 silencing, small ...
Esther Vilches‐Herrando, Guillermo Rodríguez‐Bey, Rosendo G. Hernández, Ángela Gento‐Caro, Ángel M. Pastor, Antonio Campos‐Caro, David González‐Forero, Bernardo Moreno‐López   +7 more
wiley   +1 more source

Mechanisms of resistance to antibody-drug conjugates in cancer therapy: molecular basis and therapeutic strategies. [PDF]

Cancer Drug Resist
Hao Y, Song Z.
europepmc   +1 more source

HLA‐DRB1 Allelic Combinations Differentially Shape Dendritic Cell Antigen Presentation Enhanced by Tumour Cell Line Lysate‐Pulsing

HLA, Volume 107, Issue 2, February 2026.
ABSTRACT The anti‐tumour immune response plays a pivotal role in eliminating tumour cells, with the presence of tumour‐infiltrating lymphocytes (TILs) often correlated with improved patient outcomes. Among these, CD4+ T lymphocytes act as key orchestrators of the immune response, functioning as effector and regulatory cells, and are essential for ...
Gonzalo Lázaro, Juan A. Cedano, Maitane Faus, Carme Roura‐Mir, Laia Garrigós, José Pérez‐García, Javier Román‐García, Javier Cortés, Andrea Aran, Mercè Martí   +9 more
wiley   +1 more source

Mechanism of Growth Phase-Dependent Nanoplastic Bioaccumulation in <i>Tetrahymena thermophila</i>. [PDF]

Antioxidants (Basel)
Jiang Z, Wei T, Tong H, Xing R, Peng D, Yuan T, Zhao L, Min M, Guo W.   +8 more
europepmc   +1 more source

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai, Dongjie Sun, Yanxiao Zhao, Mengtao Zhang, Yifan Wu, Jiabo Ding   +5 more
wiley   +1 more source

The actin nucleation promoting factor WASH facilitates clathrin-independent endocytosis of human papillomaviruses. [PDF]

EMBO Rep
Brinkert P, Krebs L, Samperio Ventayol P, Greune L, Bannach C, Amakiri C, Bucher D, Kollasser J, Dersch P, Boulant S, Stradal TEB, Schelhaas M.   +11 more
europepmc   +1 more source

Polysaccharide‐Coated ETCA Nanoparticles Containing the Methoxyl Substituted Indole‐Thiazole Derivative and Their Antiproliferative Activity in Breast Cancer Cells

Journal of Applied Polymer Science, Volume 143, Issue 4, January 20, 2026.
ABSTRACT Indole and thiazole derivatives have garnered significant attention due to their potent antitumor activities. Encapsulation of such derivatives into polymeric nanoparticles offers several advantages, including improved molecular stability and targeted delivery to tumor sites, thereby enhancing their antineoplastic potential.
José Cleberson Santos Soares, Iago Dillion Lima Cavalcanti, Iranildo José da Cruz‐Filho, Mariane Cajubá de Britto Lira Nogueira, Maria do Carmo Alves de Lima   +4 more
wiley   +1 more source