Results 231 to 240 of about 3,012,914 (272)
Iron uptake from transferrin and transferrin endocytic cycle in friend erythroleukemia cells
AbstractSeveral aspects of iron metabolism were studied in cultured Friend erythroleukemia cells before and after induction of hemoglobin synthesis by dimethyl sulfoxide. The maximal rate of iron uptake from 59Fe‐labeled transferrin, 1.5 × 106 atoms of Fe/cell per 30 min in uninduced cells, increased to 3 × 106 atoms/cell after 5 days of induction. The
A Hradílek, J Neuwirt
semanticscholar +4 more sources
Dynamics of the orphan myosin MyoF over Trypanosoma cruzi life cycle and along the endocytic pathway
Trypanosoma cruzi proliferative forms perform endocytosis through a specialized structure named the cytostome-cytopharynx complex (SPC). The SPC is a specialized invagination of the cell membrane that extends through the cell body towards the posterior regions, with its aperture close to the flagellar pocket. Recently, diverse proteins were found along
Aline Araujo Alves +5 more
semanticscholar +4 more sources
Optimal control of receptor reinsertion in the Low Density Lipoprotein endocytic cycle
On the basis of this study, it is concluded that within physiological limits the minimum value for the mean capture time of LDL receptors by coated pits must be induced fundamentally by an optimal characterization of their insertion rate function. The corresponding steady-state surface aggregation patterns for the unbound receptors are consistent with ...
Héctor Echavarría-Heras
semanticscholar +4 more sources
Synaptic vesicles retain their identity through the endocytic cycle
After fusion of synaptic vesicles with presynaptic membrane and secretion of the contents of the vesicles into the synaptic cleft (a process known as exocytosis), the vesicular membrane is retrieved by endocytosis (internalization) for re-use. Several issues regarding endocytosis at central synapses are unresolved, including the location of membrane ...
Venkatesh N. Murthy, Charles F. Stevens
semanticscholar +4 more sources
The synapsin cycle: A view from the synaptic endocytic zone
AbstractAlthough the synapsin phosphoproteins were discovered more than 30 years ago and are known to play important roles in neurotransmitter release and synaptogenesis, a complete picture of their functions within the nerve terminal is lacking. It has been shown that these proteins play an important role in the clustering of synaptic vesicles (SVs ...
Emma Evergren +2 more
semanticscholar +6 more sources
A Whole Cell Kinetic Model of the Endocytic Cycle: Focus on Sorting
In Chapters 3 and 4, equilibrium and kinetic schemes were examined in order to elucidate the mechanism by which receptors and ligands are sorted in the endosome. The most successful of these mechanisms, in terms of explaining the efficient recycling of receptors from the endosome back to the cell surface, suggested that receptors diffuse from the ...
Jennifer J. Linderman +1 more
semanticscholar +3 more sources
Inhibition of endocytic vesicle fusion in vitro by the cell-cycle control protein kinase cdc2
Membrane transport between the endoplasmic reticulum and the plasma membrane, which involves the budding and fusion of carrier vesicles, is inhibited during mitosis in animal cells. At the same time, the Golgi complex and the nuclear envelope, as well as the endoplasmic reticulum in some cell types, become fragmented.
Teppo Tuomikoski +3 more
semanticscholar +4 more sources
WITHDRAWN: A Role for Endocytic Cycling in Hyphal Growth
Available online. This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy .
Brian D. Shaw +4 more
openalex +2 more sources
ABSTRACT We describe a detailed morphological characterization of the endocytic pathway in differentiating chicken erythroblasts transformed by a temperature-sensitive mutant of avian erythroblastosis virus (AEV). These cells express high levels of transferrin receptors (TfR) when induced to differentiate at 42°C.
Iris Killisch +5 more
openalex +3 more sources
RAP1A protein is a small Ras-like GTPase that accumulates during muscle differentiation. In this study, we observed variable intracellular location of the endogenous RAP1A protein and concomitant relocation of the late endocytic compartments in differentiating myogenic cells. By monitoring the nucleotide-bound form of RAP1A protein, we established that
Véronique Pizon +2 more
openalex +3 more sources

