Isolation and characterization of a functionally active protein translocation apparatus from chloroplasts envelopes [PDF]
Morré, D. James+2 more
core
Autosomal Recessive Cerebellar Ataxias: Translating Genes to Therapies
[Color figure can be viewed at www.annalsofneurology.org] Autosomal recessive cerebellar ataxias are disabling neurodegenerative genetic conditions affecting balance and coordination. Advancements in genomic testing have improved diagnosis, leading to a new focus on the development of targeted precision therapeutics addressing cellular, biochemical ...
Brent L. Fogel+10 more
wiley +1 more source
Extracellular Vesicles in Arthropods: Biogenesis, Functions, Isolation Methods and Applications
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound nanoparticles secreted by cells that are involved in multiple forms of intercellular communication and show promising potential for biotechnological applications. Arthropod‐derived EV research remains relatively fragmented in contrast to the extensively studied mammalian EV field. In this review,
Simon Remans+3 more
wiley +1 more source
Exploring potential therapeutic targets for small cell lung cancer based on transcriptomics combined with Mendelian randomization analysis. [PDF]
Liao Z, Jia P, Li Y, Zheng Z, Zhang J.
europepmc +1 more source
Host Ferritin Translocates into the Chlamydial Inclusion: A Clear Alteration in its Subcellular Distribution as a Result of Infection [PDF]
Al-Younes, H., Meyer, T.
core +1 more source
ABSTRACT Pregnancy and live birth rates are commonly used metrics to define fertility in humans and animals. The impact of aberrant microRNA (miRNA) expression on fertility‐related genes represents a significant knowledge gap in understanding post‐transcriptional regulatory mechanisms associated with reproductive dysfunction.
Pevindu Abeysinghe+5 more
wiley +1 more source
Ferroptosis in Cancer and Inflammatory Diseases: Mechanisms and Therapeutic Implications
Ferroptosis, a form of cell death driven by iron and lipid peroxidation, serves as a bridge between cancer and inflammatory diseases. Microenvironmental factors such as oxidative stress collectively regulate this process. In cancer, ferroptosis exhibits dual roles: while it eliminates drug‐resistant cells, it may also promote tumor metastasis.
Guangyi Shen+4 more
wiley +1 more source
Asialoglycoprotein receptor 1: a multifaceted receptor in the liver and cardiovascular system. [PDF]
Xiao X, Nie Y, Leng Y.
europepmc +1 more source
Recent Progress in Gene Delivery Systems Based on Gemini‐Surfactant
Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating genes. The low micelle concentration, effective nucleic acid complexation, and low immunogenicity make Gemini surfactants promising gene delivery vectors.
Peng Qian+5 more
wiley +1 more source