Results 21 to 30 of about 3,012,914 (272)
Journal of Biological Chemistry, 1993 The prion protein (PrPC) is a glycolipid-anchored, cell surface protein of unknown function, a posttranslationally modified isoform of which has been implicated in the pathogenesis of spongiform encephalopathies in man and animals. We report here the novel observation that chPrP, the chicken homologue of mammalian PrPC, constitutively cycles between ...
Show‐Ling Shyng +2 more
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C1q drives neural stem cell quiescence by regulating cell cycle and metabolism through BAI1 [PDF]
Nature CommunicationsC1q levels in the CNS are elevated by inflammation and neurovascular trauma, yet the consequence of this increase for neural stem cell (NSC) regeneration response remain unknown.
Katja M. Piltti +16 more
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Molecular Biology of the Cell, 2000 In the present study, we show that in human endothelial cells the tetraspanin CD63/lamp3 distributes predominantly to the internal membranes of multivesicular–multilamellar late endosomes, which contain the unique lipid lysobisphosphatidic acid. Some CD63/lamp3 is also present in Weibel–Palade bodies, the characteristic secretory organelle of these ...
Toshihide Kobayashi +7 more
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Lysosome assembly and disassembly changes endocytosis rate through the Leishmania cell cycle
MicrobiologyOpen, 2020 The Leishmania lysosome has an atypical structure, consisting of an elongated vesicle‐filled tubule running along the anterior–posterior axis of the cell, which is termed the multivesicular tubule (MVT) lysosome.
Ziyin Wang +2 more
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Cell-cycle-dependent trafficking in the endocytic pathway
, 2008 In the endocytic pathway, many components are degraded. This is essential for cells in many ways, like uptake of nutrients, defense against pathogens, receptor downregulation, and antigen processing. In interphase, the endocytic pathway is highly dynamic and receives components both from the plasma membrane and from the trans-Golgi network. In mitosis,
Trygve Bergeland
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Proteomics of secretory and endocytic organelles in Giardia lamblia. [PDF]
PLoS ONE, 2014 Giardia lamblia is a flagellated protozoan enteroparasite transmitted as an environmentally resistant cyst. Trophozoites attach to the small intestine of vertebrate hosts and proliferate by binary fission.
Petra B Wampfler +4 more
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2007 Johannes Hell
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Rossijskij fiziologičeskij žurnal im. I.M. SečenovaUsing fluorescence microscopy, we studied the participation of Ca2+-acceptor proteins in the processes of the exo-endocytotic cycle of neurotransmitter quantal secretion in the neuromuscular junction of the somatic muscle of the earthworm Lumbricus terrestris. Inhibition of calcineurin, calmodulin and Ca2+/calmodulin dependent protein kinases led to an
Л. Ф. Нуруллин +2 more
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Biophysical Reports, 2022 While exposure of C17.2 neural progenitor cells (NPCs) to nanomolar concentrations of carbon nanotubes (NTs) yields evidence of cellular substructure reorganization and alteration of cell division and differentiation, the mechanisms of NT entry are not ...
Swetha Chandrasekar +5 more
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Identification and characterization of an unusual class I myosin involved in vesicle traffic in Trypanosoma brucei. [PDF]
PLoS ONE, 2010 Myosins are a multimember family of motor proteins with diverse functions in eukaryotic cells. African trypanosomes possess only two candidate myosins and thus represent a useful system for functional analysis of these motors.
Diana Spitznagel +4 more
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