Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer [PDF]
Lysosomal storage is the most common cause of neurodegenerative brain disease in preadulthood. However, the underlying cellular mechanisms that lead to neuronal dysfunction are unknown.
Bellen, Hugo J+7 more
core +3 more sources
Flowering time modulation by a vacuolar SNARE via FLOWERING LOCUS C in Arabidopsis thaliana. [PDF]
The transition of plant growth from vegetative to reproductive phases is one of the most important and dramatic events during the plant life cycle.
Kazuo Ebine+3 more
doaj +1 more source
Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska+75 more
core +6 more sources
Background: Recurrent implantation failure (RIF) remains a critical and challenging problem in assisted reproductive technology mainly due to impaired decidualization.
Quan Zhou+12 more
doaj +1 more source
Hormone-stimulated modulation of endocytic trafficking in osteoclasts [PDF]
Copyright @ 2012 Stenbeck, Lawrence and Albert. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in other forums, provided the original authors and ...
Albert, AP, Lawrence, KM, Stenbeck, G
core +2 more sources
Antigen capturing at the periphery is one of the earliest, crucial functions of antigen-presenting cells (APCs) to initiate immune responses. Langerhans cells (LCs), the epidermal APCs migrate to draining lymph nodes (DLNs) upon acquiring antigens.
Miguel Angel Becerril-García+11 more
doaj +1 more source
Mg-rich amorphous to Mg-low crystalline CaCO3 pathway in foraminifera
Calcium carbonate minerals produced by marine organisms play a central role in the global carbon cycle and carbonate sedimentation, which influence the climate by regulating atmospheric CO2 levels.
Zofia Dubicka+3 more
doaj +1 more source
Interaction of CK1δ with γTuSC ensures proper microtubule assembly and spindle positioning. [PDF]
Casein kinase 1δ (CK1δ) family members associate with microtubule-organizing centers (MTOCs) from yeast to humans, but their mitotic roles and targets have yet to be identified.
Agard, David A+10 more
core +1 more source
Structural organization of Trypanosoma cruzi
Since the initial description of Trypanosoma cruzi by Carlos Chagas in 1909, several research groups have used different microscopic techniques to obtain detailed information about the various developmental stages found in the life cycle of this ...
Wanderley de Souza
doaj +1 more source
ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei. [PDF]
We have previously identified homologs for nearly half of the approximately 30 known yeast Atg's in the genome database of the human sleeping sickness parasite Trypanosoma brucei.
Ana Brennand+5 more
doaj +1 more source