Results 41 to 50 of about 3,012,914 (272)

Eng2, a new player involved in feedback loop regulation of Cdc42 activity in fission yeast

Scientific Reports, 2021
Cell polarity and morphogenesis are regulated by the small GTPase Cdc42. Even though major advances have been done in the field during the last years, the molecular details leading to its activation in particular cellular contexts are not completely ...
Patricia García, Pedro M. Coll, Francisco del Rey, M. Isabel Geli, Pilar Pérez, Carlos R. Vázquez de Aldana, Javier Encinar del Dedo   +6 more
doaj   +1 more source

Specific Endocytosis Blockade of Trypanosoma cruzi Exposed to a Poly-LAcNAc Binding Lectin Suggests that Lectin-Sugar Interactions Participate to Receptor-Mediated Endocytosis.

PLoS ONE, 2016
Trypanosoma cruzi is a protozoan parasite transmitted by a triatomine insect, and causing human Chagas disease in South America. This parasite undergoes a complex life cycle alternating between non-proliferative and dividing forms.
Sébastien Brosson, Frédéric Fontaine, Marjorie Vermeersch, David Perez-Morga, Etienne Pays, Sabrina Bousbata, Didier Salmon   +6 more
doaj   +1 more source

Transcriptomic and metabolomic analyses reveal the essential nature of Rab1B in Toxoplasma gondii

Parasites & Vectors, 2023
Background The protozoan parasite Toxoplasma gondii encodes a dozen Rab proteins, which are parts of the small GTPase superfamily and regulate intracellular membrane trafficking.
Kai He, Qiangqiang Wang, Xuwen Gao, Tao Tang, Huiyong Ding, Shaojun Long   +5 more
doaj   +1 more source

miR-17-5p regulates endocytic trafficking through targeting TBC1D2/Armus.

PLoS ONE, 2012
miRNA cluster miR-17-92 is known as oncomir-1 due to its potent oncogenic function. miR-17-92 is a polycistronic cluster that encodes 6 miRNAs, and can both facilitate and inhibit cell proliferation.
Andrius Serva, Bettina Knapp, Yueh-Tso Tsai, Christoph Claas, Tautvydas Lisauskas, Petr Matula, Nathalie Harder, Lars Kaderali, Karl Rohr, Holger Erfle, Roland Eils, Vania Braga, Vytaute Starkuviene   +12 more
doaj   +1 more source

Flowering time modulation by a vacuolar SNARE via FLOWERING LOCUS C in Arabidopsis thaliana. [PDF]

PLoS ONE, 2012
The transition of plant growth from vegetative to reproductive phases is one of the most important and dramatic events during the plant life cycle.
Kazuo Ebine, Tomohiro Uemura, Akihiko Nakano, Takashi Ueda   +3 more
doaj   +1 more source

Dysregulation of the AP2M1 phosphorylation cycle by LRRK2 impairs endocytosis and leads to dopaminergic neurodegeneration

Science Signaling, 2021
Clathrin-mediated endocytosis in neurons is sensitive to the abundance and activity of the kinase LRRK2. LRRK2 links endocytosis to Parkinson’s disease Defects in endocytosis and mutations in the kinase LRRK2 are associated with Parkinson’s disease.
Qinfang Liu, Judith Bautista-Gomez, D. Higgins, Jianzhong Yu, Yulan Xiong   +4 more
semanticscholar   +1 more source

EHD1 impairs decidualization by regulating the Wnt4/β-catenin signaling pathway in recurrent implantation failure

EBioMedicine, 2019
Background: Recurrent implantation failure (RIF) remains a critical and challenging problem in assisted reproductive technology mainly due to impaired decidualization.
Quan Zhou, Guijun Yan, Lijun Ding, Jingyu Liu, Xiaoying Yu, Shuangbo Kong, Mei Zhang, Zhilong Wang, Yang Liu, Yue Jiang, Na Kong, Jianxin Sun, Haixiang Sun   +12 more
doaj   +1 more source

Langerhans Cells From Mice at Birth Express Endocytic- and Pattern Recognition-Receptors, Migrate to Draining Lymph Nodes Ferrying Antigen and Activate Neonatal T Cells in vivo

Frontiers in Immunology, 2020
Antigen capturing at the periphery is one of the earliest, crucial functions of antigen-presenting cells (APCs) to initiate immune responses. Langerhans cells (LCs), the epidermal APCs migrate to draining lymph nodes (DLNs) upon acquiring antigens.
Miguel Angel Becerril-García, Juan Carlos Yam-Puc, Juan Carlos Yam-Puc, Raúl Maqueda-Alfaro, Nonantzin Beristain-Covarrubias, Monica Heras-Chavarría, Isis Amara Gallegos-Hernández, Juana Calderón-Amador, Rosario Munguía-Fuentes, Luis Donis-Maturano, Adriana Flores-Langarica, Leopoldo Flores-Romo   +11 more
doaj   +1 more source

Structural organization of Trypanosoma cruzi

Memorias do Instituto Oswaldo Cruz, 2009
Since the initial description of Trypanosoma cruzi by Carlos Chagas in 1909, several research groups have used different microscopic techniques to obtain detailed information about the various developmental stages found in the life cycle of this ...
Wanderley de Souza
doaj   +1 more source

Mg-rich amorphous to Mg-low crystalline CaCO3 pathway in foraminifera

Heliyon, 2023
Calcium carbonate minerals produced by marine organisms play a central role in the global carbon cycle and carbonate sedimentation, which influence the climate by regulating atmospheric CO2 levels.
Zofia Dubicka, Maciej J. Bojanowski, Jelle Bijma, Ulf Bickmeyer   +3 more
doaj   +1 more source