Results 51 to 60 of about 3,012,914 (272)
ATG24 Represses Autophagy and Differentiation and Is Essential for Homeostasy of the Flagellar Pocket in Trypanosoma brucei. [PDF]
PLoS ONE, 2015 We have previously identified homologs for nearly half of the approximately 30 known yeast Atg's in the genome database of the human sleeping sickness parasite Trypanosoma brucei.
Ana Brennand +5 more
doaj +1 more source
Medical Oncology, 2021 Non-visual arrestins (β-arrestins) are endocytic proteins that mediate agonist-activated GPCRs internalization and signaling pathways in an independent manner. The involvement of β-arrestins in cancer invasion and metastasis is increasingly reported. So,
Thoria Donia +3 more
semanticscholar +1 more source
Volleying plasma membrane proteins from birth to death: Role of J-domain proteins
Frontiers in Molecular Biosciences, 2022 The function, stability, and turnover of plasma membrane (PM) proteins are crucial for cellular homeostasis. Compared to soluble proteins, quality control of plasma membrane proteins is extremely challenging.
Preeti Sagarika +2 more
doaj +1 more source
Role of Phosphorylation in the Control of Clathrin-Mediated Internalization of GPCR
International Journal of Cell Biology, 2011 The process by which G protein-coupled receptors (GPCRs) are internalized through the clathrin-coated vesicles involves interactions of multifunctional adaptor proteins.
Frederic Delom, Delphine Fessart
doaj +1 more source
Reovirus Cell Entry Requires Functional Microtubules
mBio, 2013 Mammalian reovirus binds to cell-surface glycans and junctional adhesion molecule A and enters cells by receptor-mediated endocytosis in a process dependent on β1 integrin.
Bernardo A. Mainou +5 more
doaj +1 more source
The redox sensor TXNL1 plays a regulatory role in fluid phase endocytosis. [PDF]
PLoS ONE, 2007 BACKGROUND: Small GTPases of the Rab family can cycle between a GTP- and a GDP-bound state and also between membrane and cytosol. The latter cycle is mediated by the Guanine Nucleotide Dissociation Inhibitor GDI, which can selectively extract GDP-bound ...
Michela Felberbaum-Corti +4 more
doaj +1 more source
Wellcome Open Research, 2023 Background: Genome-wide subcellular protein localisation in Trypanosoma brucei, through our TrypTag project, has comprehensively dissected the molecular organisation of this important pathogen. Powerful as this resource is, T.
Richard J. Wheeler +3 more
doaj +1 more source
The Intracellular Life Cycle of Brucella spp
Microbiology spectrum, 2019 Bacteria of the genus Brucella colonize a wide variety of mammalian hosts, in which their infectious cycle and ability to cause disease predominantly rely on an intracellular lifestyle within phagocytes.
J. Celli
semanticscholar +1 more source
Insights into the function of ESCRT complex and LBPA in ASFV infection
Frontiers in Cellular and Infection Microbiology, 2023 The African swine fever virus (ASFV) is strongly dependent on an intact endocytic pathway and a certain cellular membrane remodeling for infection, possibly regulated by the endosomal sorting complexes required for transport (ESCRT).
Lucía Barrado-Gil +4 more
doaj +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source