Results 231 to 240 of about 249,281 (299)

DNA methylation-mediated suppression of endocytosis confers resistance to duck hepatitis A virus type 3. [PDF]

Microbiol Spectr
Li S, Hu D, Mei X, Kinkpe L, Wang S, Wei J, Hou S, Zhang Y, Wang X.   +8 more
europepmc   +1 more source

Relevance of potential endocytosis motifs in Cedar virus glycoprotein G for its biological activity. [PDF]

J Virol
Burrer C, Hund I, Rüdiger C, Reiche S, Groschup MH, Tews BA, Ushakov DS, Fischer K, Diederich S.   +8 more
europepmc   +1 more source

SIRT7‐Mediated H2BK120 Succinylation Drives Aberrant Mitophagy in Sepsis‐Associated Cognitive Dysfunction

Advanced Science, EarlyView.
Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng, Jiateng Zhou, Xiaoyu Guo, Ting Hong, Xuelian Li, Xingyu Wei, Chanhua Zhang, Xixue Zhang, Songbin Liu, Yulin Zhang, Liangfang Yao, Lina Huang, Weidong Gu   +12 more
wiley   +1 more source

Erratum to: Golgi phosphoprotein 3 promotes glioma progression via inhibiting Rab5-mediated endocytosis and degradation of epidermal growth factor receptor. [PDF]

Neuro Oncol
europepmc   +1 more source

FCHO1 fine-tunes synaptic vesicle endocytosis in an activity-dependent manner. [PDF]

Mol Brain
Lee HJ, Lee W, Kim SH.
europepmc   +1 more source

An Unbiased Geometry‐Resolved Membrane Platform for Proteome‐Scale Discovery of Membrane Curvature Sensors

Advanced Science, EarlyView.
A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa, Rikuto Kawakami, Kunanon Chattrairat, Tatsuya Niwa, Taiga Ajiri, Takao Yasui, Masayoshi Tanaka   +6 more
wiley   +1 more source

Seeing the Chemistry of Biomolecular Condensates: In Situ Mapping of Composition and Water Content

Advanced Science, EarlyView.
Raman hyperspectral imaging combined with spectral phasor analysis enables a label‐free quantification of proteins, polymers and water density within individual biomolecular condensates. By transforming complex vibrational fingerprints into intuitive compositional maps, the approach reveals the high water content and structural heterogeneity of ...
E. Sabri, A. Mangiarotti, C. N. Z. Schmitt, R. Dimova   +3 more
wiley   +1 more source

Effect of Endocytosis Inhibitors on the Cytotoxicity and Antitumor Activity of Anti-GD2 ADCs. [PDF]

Acta Naturae
Titov MM, Kholodenko IV, Kalinovsky DV, Makarova AO, Ryazantsev DY, Svirshchevskaya EV, Deyev SM, Kholodenko RV.   +7 more
europepmc   +1 more source

Targeted Lysosomal Degradation of Extracellular and Membrane Proteins: From Receptor Hijacking to Programmable Endolysosomal Routing

Advanced Science, EarlyView.
Targeted chimeric degraders engage extracellular or membrane proteins and endocytosable cell‐surface receptors, forming ternary complexes that induce receptor‐mediated internalization. Following endocytosis, post‐endocytic sorting—not internalization alone—determines target fate.
Ke Liu, Xiyan Wang, Xiaozhen Liu, Chaoqi He, Da Qian, Xuli Meng, Liquan Zhu   +6 more
wiley   +1 more source

Endolysosomal two-pore channels regulate a conserved entry pathway for enteroviruses. [PDF]

J Gen Virol
Weng TC, Hsu BY, Wu TH, Gu XY, Cheng HH, Kung SH.   +5 more
europepmc   +1 more source