Results 271 to 280 of about 342,266 (343)

Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation

Advanced Science, EarlyView.
Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim, Gyeongseok Yang, Chaelyeong Lim, Gaeun Park, Jaemo Lee, Youjung Sim, Ja‐Hyoung Ryu   +6 more
wiley   +1 more source

Intravesical Tumor-Selective Mucoadhesive Hydrogel for Effective Chemotherapy In Murine Model. [PDF]

Int J Nanomedicine
Zheng B, Chen Z, Sun L, Quan J, Wei J, Huang B, Zhang D, Zhang P, Zhuo Y.   +8 more
europepmc   +1 more source

Machine Learning‐Enhanced Nanoparticle Design for Precision Cancer Drug Delivery

Advanced Science, EarlyView.
Machine Learning (ML) is revolutionizing cancer nanomedicine by optimizing nanoparticle (NP) design and drug delivery. This review summarizes ML applications across all stages of NP drug delivery, along with a discussion of ongoing challenges and future directions.
Qingquan Wang, Yujian Liu, Chenchen Li, Bin Xu, Shidang Xu, Bin Liu   +5 more
wiley   +1 more source

Transferrin receptors. [PDF]

Exp Mol Med
Guo Q, Qian C, Wang X, Qian ZM.
europepmc   +1 more source

A pool of intracellular phosphorylated asialoglycoprotein receptors which is not involved in endocytosis.

, 1991
Willem Stoorvogel, Anna L. Schwartz, Ger J. Strous, Robert J. Fallon   +3 more
openalex   +1 more source

Manipulating Liquid‐Liquid Interphase Solute Diffusion for the Construction of Non‐Symmetric Metal‐Quinone Network Nanoarchitectonics and Nano‐Motorization

Advanced Science, EarlyView.
Non‐symmetric metal‐quinone network (MQN) nanoarchitectonics with controllable morphology and size are constructed by manipulating interphase solute diffusion during the nanoprecipitation process. Self‐propelled nanomotors developed from non‐symmetric MQN nanoarchitectonics exhibit chemotactic autonomous motion toward overexpressed H2O2 in tumor ...
Wenzhe Xu, Yingke Xue, Yang Chen, Ruixu Yang, Shuwei Liu, Yi Liu, Hao Zhang   +6 more
wiley   +1 more source

Endocytosis of sialic acid Neu5Gc and elevated p53 contributes to preimplantation embryonic arrest during in vitro fertilization. [PDF]

J Biol Chem
Yuan X, Wu Y, Zhang Y, Yao B, Zhang L, Liu Z, Ma Q, Ma F.   +7 more
europepmc   +1 more source

Nucleic Acid‐Locked Smart Carrier for Photothermal/Chemotherapy‐Amplified Immunogenic Cell Death to Enhance Systemic Antitumor Efficacy

Advanced Science, EarlyView.
Multiple therapeutic modalities combined in a synergistic way that can modulate different immune axes are demonstrated potentially effective in boosting immunotherapy. A nucleic acid‐locked smart carrier (NASC) performed as an “all‐in‐one” nanoplatform is constructed for efficient eliciting chemo‐ and photothermal‐amplified immunogenic cell death to ...
Jiayang Zhang, Tianyu Gai, Jiwei Wang, Yucai Wu, Si‐Ming Zeng, Dongyuan Zhao, Wei Li   +6 more
wiley   +1 more source

Trafficking and Activation of <i>Henipavirus</i>, <i>Parahenipavirus,</i> and Henipa-like Virus Fusion Proteins. [PDF]

Viruses
Navaratnarajah CK, Cattaneo R.
europepmc   +1 more source

Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins.

, 1994
Jan E. Schnitzer, Philmo Oh
openalex   +1 more source