Results 271 to 280 of about 361,769 (340)

Assessing the Potential of NGF-Differentiated PC12 Cells as a Model for Synaptic Transmission. [PDF]

Mol Neurobiol
Ott G, Leuenberger J, Ntamati N, Ivanov A, Nevian T, Rostami I, Zuber B.   +6 more
europepmc   +1 more source

Microfluidic‐Driven Lipid Nanoparticles for Improved miRNA Delivery via Endo‐Lysosomal Trafficking Optimization

Advanced Science, EarlyView.
This study investigates the impact of various post‐processing methods (filtration, sonication, dialysis, and heating) on lipid nanoparticles produced using microfluidics. The nanoparticles are designed for efficient delivery of miRNA into cells. The work highlights how processing conditions influence nanoparticle stability and quality, providing ...
Alicja Kosik‐Kozioł, Michał Pruchniewski, Daniel Rybak, Piotr Jenczyk, Karolina Zakrzewska, Magdalena Bartolewska, Sławomir Błoński, Paweł Nakielski, Filippo Pierini   +8 more
wiley   +1 more source

Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL. [PDF]

Elife
Luo D, Zheng J, Lv S, Sheng R, Chen M, He X, Zhang X.   +6 more
europepmc   +1 more source

Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A‐Dependent hnRNPA2B1/COX‐2 Axis

Advanced Science, EarlyView.
Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li, Zehao Guo, Yutong Zou, Jiongfeng Zhang, Jixiang Shi, Xihong Fu, Jian Tu, Hao Yao, Xuanxuan Lu, Lili Wen, Xianbiao Xie   +10 more
wiley   +1 more source

Endophilin mediated endocytosis and epidermal growth factor receptor govern Japanese encephalitis virus entry and infection in neuronal cells. [PDF]

PLoS Pathog
Sharma P, Tanwar M, Choudhary E, Sundaram NM, Ojha D, Mishra L, Nain M, Rode A, Prasad VM, Vrati S, Kalia M.   +10 more
europepmc   +1 more source

Oral Celastrol Nanomedicine Targeting Intestinal Antigen‐Presenting Cells to Effectively Mitigate Autoimmune Uveitis via Gut‐Retina Axis

Advanced Science, EarlyView.
Oral nanoCEL exhibits effective intestinal targeting of antigen‐presenting cells and restores the Th17/Treg balance in lymph nodes and spleen, ultimately protecting the blood‐retinal barrier by inhibiting peripheral immune cell infiltration and suppressing retinal glial cell activation.
Jinrun Chen, Yuqin Wu, Bofei Xu, Jiabei Hou, Yijing Li, Yuhan Hu, Yutuo Zhu, Wenqiao Zhang, Shuqi Feng, Huanting Jin, Yuchen Cheng, Yuanyuan Jin, Jianhong Zhou, Xingyi Li   +13 more
wiley   +1 more source

A phosphoinositide switch from PI(4,5)P₂ to PI4P triggers endocytosis by inducing dynamin-mediated fission in secretory cells. [PDF]

Sci Adv
Guo X, Wei L, Kundu N, Shin W, Chan CY, Han S, Mohseni A, Molakarimi M, Sun M, Wu XS, Jin Y, Hinshaw JE, Wu LG.   +12 more
europepmc   +1 more source

Nitrogen‐Boosted H2O2 Production of Arginine‐Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration

Advanced Science, EarlyView.
PEA nanoenzymes are assembled from L‐arginine and EGCG. The nitrogen element in arginine enhances the thermodynamic feasibility of H2O2 production through PEA's oxygen reduction catalysis, enabling nitrogen‐dependent H2O2 release. Intradermal delivery of PEA via microneedles promotes efficient H2O2 synthesis, thereby stimulating regrowth in telogen ...
Yifei Wang, Yaojia Yang, Aoxue Wang, Chen Shen, Shenliang Tan, Changsheng Liu, Yuzheng Zhao, Xue Qu   +7 more
wiley   +1 more source

Tumor-Derived Microvesicles Induce Proangiogenic Phenotype in Endothelial Cells via Endocytosis [an abstract of dissertation and a summary of dissertation review]

, 2014
泰輔 川本
openalex   +1 more source